Objective To find out the situation about the Mycoplasma pneumonia infection in this area and provide the diagnosis and treatment proofs for clinic. Method Detecting the Mycoplasma pneumonia distinctive antibody IgM in 1482 respiratory infection patients' serum with the indirect agglutination test. The consistence≥1∶80 is positive,≤1:40 is negative. Result 234 of the 1482 patients are positive with MP-IgM, the positive rate is 15.79%, the highest consistence is 1:1280.The youngest who can be detected the MP-IgM is 3 months old and the oldest is 83 years old. There isn't remarkable difference between man and woman but the age and season have great influence in the positive rate, p0.01. Conclusion Mycoplasma pneumonia can cause respiratory infection all the seasons, the positive rate is especially high in winter and spring, 6 to 14 years old children have the highest incidence. MP-IgM should be more detected in respiratory infection patients so as to provide the diagnosis and treatment proofs for clinic, avoid abusing antibiotic. Detecting MP-IgM with the indirect agglutination test is easy, quick and suitable for clinic.