The purpose of the study is to evaluate the safety, feasibility and applicability of a new device 'Tampostat' in the management of primary postpartum hemorrhage and compare the efficacy of 'Tampostat' in terms of arresting primary PPH with that of the conventional condom catheter.

Start Date01 Apr 2015

Sponsor / Collaborator

International Centre for Diarrhoeal Disease Research, Bangladesh

[+4]

NCT01328457

/ CompletedNot ApplicableIIT

An Effectiveness Study of Paromomycin IM Injection (PMIM) for the Treatment of Visceral Leishmaniasis (VL) in Bangladesh

The purpose of this study is to evaluate the effectiveness of treatment with PMIM in patients with visceral leishmaniasis within the VL-endemic region of Bangladesh at EOT (21/22 days after treatment begins), and at 6 months after end of treatment (Day 202/203, -15 to +30 days).

Start Date01 Jan 2011

Sponsor / Collaborator

Program for Appropriate Technology in Health

[+3]

NCT01122771

/ CompletedPhase 3IIT

A Phase III, Open Label, Randomised, Study of Three Short Course Combination Regimens (Ambisome®, Miltefosine, Paromomycin) Compared With AmBisome® Alone for the Treatment of Visceral Leishmaniasis (VL) in Bangladesh

This protocol will evaluate the efficacy and safety of various combinations of the three drugs; AmBisome, Paromomycin and Miltefosine at reduced total dosage against the standard treatment with a total dose of 15mg/kg of AmBisome.

Start Date01 May 2010

Sponsor / Collaborator

Drugs for Neglected Diseases initiative

[+2]

100 Clinical Results associated with Shaheed Suhrawardy Medical College & Hospital

0 Patents (Medical) associated with Shaheed Suhrawardy Medical College & Hospital

538

Literatures (Medical) associated with Shaheed Suhrawardy Medical College & Hospital

01 Jun 2025·International Journal of Cardiology Cardiovascular Risk and Prevention

Cardiovascular risk in newly diagnosed patients with type 2 diabetes mellitus: a nationwide, facility-based, cross-sectional study in Bangladesh

Article

Author: Ahmad, Shahryar ; Singha, Swapan Kumar ; Raunak, Ahmed Ifrad Bin ; Mondal, Ershad ; Gaffar, Md Abu Jar ; Hoque, Md Azizul ; Rahman, Md Shahinur ; Selim, Shahjada ; Mustari, Marufa ; Robel, Md Abdul Bari ; Rahman, Mohammad Motiur ; Kaisar, Md Mostofa ; Hannan, Mohammad Abdul ; Kamrul-Hasan, A B M ; Nur-A-Musabber ; Sarker, Sourav ; Chowdhury, Sumon Rahman ; Islam, Md Rashedul ; Alam, Muhammad Shah ; Chowdhury, Emran Ur Rashid ; Mohana, Choman Abdullah

AimsEvidence on cardiovascular (CV) risk stratification in Bangladeshi patients with type 2 diabetes mellitus (T2DM) who are asymptomatic for cardiovascular disease (CVD) is limited. This study aimed to assess the 10-year CV risk in newly diagnosed patients with T2DM.MethodsIn 2023, a cross-sectional study was carried out at endocrinology clinics in tertiary hospitals throughout Bangladesh, involving newly diagnosed patients with T2DM aged 25 to 84 who had no prior history of CVD and were asymptomatic for the condition. CV risk was assessed and classified using QRISK3.Results1617 newly diagnosed patients with T2DM (age 44.92 ± 11.84 years, male 49.5 %) were analyzed. Their median QRISK3 score was 11.0 %, with 46.5 % at low, 25.7 % at moderate, and 27.8 % at high 10-year CV risk, respectively. The QRISK3 score increased with age for both men and women, with men consistently scoring higher than women in every age group. Among the age groups 25-39, 40-64, and 65-84, the percentages of patients with high 10-year CV risk were 3.3 %, 34.0 %, and 94.5 %, respectively. The median relative risk (RR) of CVD was 4.3. RR decreased with age for both sexes, and men had a lower RR than women across all age groups. A sleep duration of 6-9 h was associated with a lower 10-year CV risk.ConclusionsMany newly diagnosed Bangladeshi patients with T2DM have substantial CV risk. QRISK3 can assist clinicians in predicting 10-year CV risk and choosing appropriate treatments to prevent CVD.

01 May 2025·Asian Journal of Psychiatry

A Google Trends analysis exploring public interest in common psychiatric conditions and non-pharmacological interventions

Article

Author: Paul, Ponnu Maria ; Minn, Su W ; See, Jia Whei ; Tariq, Daaniya ; Ndubueze, Chidera

BACKGROUND AND OBJECTIVESTo use Google Trends for analyzing public interest in common psychiatric illnesses such as Depression, Anxiety, Bipolar Disorder, Post-traumatic Stress Disorder, and Obsessive-Compulsive Disorder, along with their various treatment modalities, in the United States over the past 10 years, in order to provide insights into emerging treatment modalities and their popularity among the population.METHODOLOGYA cross-sectional study was conducted from May 7 to June 6, 2024, using Google Trends data, specifically Relative Search Volume (RSV) from 2014 to 2023. Relative Search Volume is a metric provided by Google Trends, it is normalized to a scale of 0-100, where 100 represents the peak popularity of a search item within the selected time frame and location. Various psychological diseases and treatment modalities were searched individually, with all data and statistical analysis performed using Microsoft Excel and R v4.3.2.RESULTSThe analysis revealed an overall increase in annual search interest for various mental health conditions, with Anxiety peaking in 2023 and Depression reaching its highest Relative Search Volume (RSV) in 2019. While Bipolar Disorder (BPD), Obsessive-Compulsive Disorder (OCD), and Post-Traumatic Stress Disorder (PTSD) also showed an upward trend, their increases were less pronounced. Additionally, search interest in therapeutic interventions, including Cognitive Behavioral Therapy (CBT), Psychotherapy, and Dialectical Behavioral Therapy (DBT), significantly increased from 2019 to 2023 compared to 2014-2018 (p < 0.05). In contrast, Electroconvulsive Therapy (ECT) had higher search frequency in the earlier period. These findings suggest a growing public interest in mental health conditions and evidence-based treatment options in recent years.CONCLUSIONSLimitations of this study include the use of Google Trends data, which relies on RSV rather than absolute search counts, which may not fully capture the extent of public interest. Additionally, the data cannot differentiate whether the searches were made by patients or healthcare professionals. However, the study's findings reflect a growing recognition and acceptance of diverse treatment approaches for mental health conditions, and concludes that while Google Trends is useful for analyzing public interest in psychiatric illnesses, further research is needed to ensure the reliability of the results.

01 Apr 2025·Annals of Medicine & Surgery

Evaluating the effectiveness of nicardipine prolonged-release implants in patients with subarachnoid hemorrhage: a meta-analysis and meta-regression analysis

Article

Author: Islam, M Rafiqul ; Khalil, Ibrahim ; Hossain, Imran ; Joy, Arindam Das

Introduction and importance:Subarachnoid hemorrhage (SAH) is a critical condition with high morbidity and mortality, often complicated by cerebral vasospasm and delayed cerebral ischemia (DCI). Nicardipine, a calcium channel blocker, has shown promise in mitigating these risks. This meta-analysis evaluates the effectiveness and safety of nicardipine prolonged-release implants in reducing SAH complications.Methods:A comprehensive literature search was conducted in PubMed, Cochrane Library, Embase, and ClinicalTrials.gov, identifying seven eligible studies involving 775 patients with SAH. Randomized controlled trials (RCTs) and observational studies were included. The primary outcome was the incidence of cerebral vasospasm, while secondary outcomes included DCI and delayed ischemic neurologic deficit (DIND). Risk ratios (RR) with 95% confidence intervals (CI) were calculated using random-effects meta-analysis.Results:Nicardipine implants significantly reduced the risk of cerebral vasospasm (RR = 0.38, 95% CI [0.23, 0.61], P < 0.0001) and DCI (RR = 0.33, 95% CI [0.18, 0.58], P = 0.0002). However, no significant effect was observed on DIND (RR = 0.68, 95% CI [0.33, 1.39], P = 0.29) or functional outcomes (modified Rankin scale; RR = 2.03, 95% CI [0.85, 4.87], P = 0.11).Conclusion:Nicardipine prolonged-release implants are effective in reducing the incidence of cerebral vasospasm and DCI in SAH patients, with potential benefits in preventing these complications. However, they do not significantly impact functional outcomes, indicating the need for complementary rehabilitation strategies. Further large-scale studies are needed to confirm these findings.

100 Deals associated with Shaheed Suhrawardy Medical College & Hospital

100 Translational Medicine associated with Shaheed Suhrawardy Medical College & Hospital

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