100 Clinical Results associated with Skeletal Kinetics LLC
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Transactions of the Annual Meeting of the Society for Biomaterials
In vivo assessment of Callos/OsteoVation calcium phosphate cement containing autologous bone
Author: Delaney, D. C. ; Jalota, S. ; Yetkinler, D. N.
Pure Callos/OsteoVation shows as an excellent osteoconductive material, perfect bone apposition and some remodeling on the periphery of the cement. Callos/OsteoVation mixed with 5% by weight bone shows slightly reduced mech. strength while the remodeling rate was close to pure Callos/OsteoVation. Callos/OsteoVation mixed with 50% by weight autologous bone retains setting strength and other properties (5 MPa compressive strength) sufficient for use in most bone graft filler applications. This mixture remodels to new bone in this animal model much more rapidly than the pure Callos/OsteoVation. Autograft alone shows complete remodeling in 6 mo but does not provide any mech. strength (< 1 MPa) to the defect site.
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