Stability of Amoxicillin Dispersible Tablets (ADT) was studied, and their storage conditions and expiration date preliminarily were determinedThe expiration date was speculated through the study of the stability of prepared ADT based on quality indexes such as character, scattered uniformity, labeling quantity and release and observing its quality changes by the influence factors test, accelerated test and long-term retention sample test and the classic method of constant temperatureADT was less stable with high temperature and high humidity but of light stability.Various quality indexes were met the quality requirements in the accelerated test and long-term sample test, and the validity could be up to two years.With double aluminum packaging and a cool, dry storing place, the quality of ADT is stable during a validity period.