A review.In the last 20 years, Phosphatidylserine has been object of a large number of explotoratory pilot trials and several randomized, double blind placebo controlled clin. trials, which highlighted its utility in the management of several mental conditions and clarified the physiol. role of endogenous Phosphatidylserine.It has been shown that supplementation with Phosphatidylserine can improve memory, learning capabilities, concentration and other cognition parameter as well as management of stress and pos. influence in mood.