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Neoplasms

Radiopharmaceuticals and diagnostic agent

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Radiopharmaceuticals and diagnostic agent	1

Facial Micro-Expression Recognition (FER) presents challenges due to individual variations in emotional intensity and the complexity of feature extraction. While apex frames offer valuable emotional information, their precise role in FER remains unclear. Low-resolution facial images further degrade performance compared to high-resolution (HR) images. Existing methods, including super-resolution and convolutional neural networks, yield only moderate results. This work proposes a deep coupled AlexNet (DCAlexNet) model with a trunk network trained on multi-resolution images to extract discriminative features and a branch network for resolution-specific mapping between HR and low-resolution (LR) images. By integrating global and local facial information, DCAlexNet enhances micro-expression recognition while filtering irrelevant facial regions. The evaluations on FER2013, BU-3DFE, and Oulu-CASIA datasets demonstrate superior performance, achieving 98.3 % accuracy on FER2013, 97.2 % on BU-3DFE, and 96 % on Oulu-CASIA, with improved RMSE, RAE, and processing times.

01 Apr 2025·Plant Physiology and Biochemistry

Spatially resolved localization of Cd and Mn and their interactions in the Cd/Mn hyperaccumulator Celosia argentea Linn

Article

Author: Ullah, Habib ; Mo, Fujin ; Sunahara, Geoffrey I ; Lian, Faqin ; Yu, Hongwei ; Yu, Guo ; An, Zebing ; Jiang, Xusheng ; You, Shaohong ; Liu, Jie ; Lai, Caixing

Celosia argentea Linn. has recently been identified as a hyperaccumulator of both manganese (Mn) and cadmium (Cd). However, the mechanisms by which C. argentea tolerates Mn and Cd toxicity remain unclear. In this study, the spatial distribution of Mn and Cd and their interactions were analyzed using X-ray microfluorescence and the Leadmium Green fluorescent probe. Mn was predominantly localized along the leaf margins, particularly at the apex, whereas in the stem and root, it primarily accumulated in epidermal tissues. The distribution patterns of Mn and calcium (Ca) in C. argentea were inversely correlated, whereas Mn and iron exhibited similar trends. Cd was mainly localized in the leaf veins, vascular bundles at the stem periphery, and vascular cylinders in the roots. Exogenous Mn addition significantly enhanced the fluorescence intensity of Cd in the leaves. Following Mn addition, Cd was detected in the mesophyll tissues and both the upper and lower epidermis, in addition to the leaf veins. Interestingly, exogenous Cd addition changed the distribution pattern of Ca in the leaves of C. argentea. These findings provide novel insights into the mechanisms underlying plant tolerance to Mn and Cd toxicities and help improve the phytoextraction efficiency of Mn and Cd co-contaminated soil.

01 Apr 2025·Food Chemistry: X

Stoichiometric analysis of 20 amino acids, thermogravimetric parameters and trace elements in five types of tea from Guizhou, China, based on entropy analysis (EA) and factor cluster analysis (FCA)

Author: Huang, Chunli ; Zhou, Libing

This study employed a range of indicators, including heat of combustion, combustibility, fat content, amino acid content, ash content, crude fiber content, trace element content, and concentrations of catechins, theanine, and caffeine, to develop comprehensive evaluation systems for assessing the quality of five tea samples: Duyun Maojian tea, Liping fragrant tea, Shuicheng spring tea, Huaxi jasmine tea, and Zunyi black tea.Anal. techniques such as gray pattern recognition (GPR), gray principal component anal. (GPCA), gray factor anal. (GFA), entropy anal. (EA), and factor cluster anal. (FCA) were utilized.Based on the 42variable data, the nutritional value ranked as follows: Shuicheng spring tea > Huaxi jasmine tea > Duyun Maojian tea > Liping fragrant tea > Zunyi black tea.These findings offer significant theor. and practical insights for the determination and comprehensive evaluation of tea quality indicators, contributing to scientific research on the nutrition, health, and classification aspects of tea.

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100 Translational Medicine associated with Guangxi Science & Technology Normal University

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Pipeline

Pipeline Snapshot as of 01 Aug 2025

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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