Delving into the Latest Updates on Avacta Analytical Ltd. with Synapse

Overview

A review.An increasing desire to deliver therapeutic proteins as liquid formulations for self-administration by patients has led to an increased need to develop mols. and formulations that are stable for several years when stored in solution in a refrigerator.Formation of protein aggregates during storage is of increasing concern to developers and regulators.Measurements that predict how stable a given protein and formulation will be during long-term storage are desirable to effectively screen and optimize candidate proteins and formulations early in the development process.The author reviews the scientific literature and examines multiple routes to aggregation during storage to suggest that multiple measurement types should be made to probe different aspects of protein behavior.

NMR and complex mixtures

Author: McRae, Cassey

A review.In this paper we have shown here that NMR can be applied to investigate the response of biol. systems to pathophysiol. stimuli by measuring the levels of metabolites and lipids in biofluids and tissues.This paper discusses NMR and complex mixtures

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