🚀 Madrigal Pharmaceuticals’ MASH drug beats expectations:
The biotech’s Rezdiffra sales came in at $311 million for the first quarter, surpassing analysts’ projections by about $10 million, according to TD Cowen analysts. The Pennsylvania drugmaker licensed another MASH drug the day before its earnings report.
— Kyle LaHucik
👥 Gilead lays off 108 workers after Arcellx buyout:
Gilead Sciences is laying off 108 staff at its newly acquired Arcellx location, according to a California WARN notice. Gilead bought its collaborator Arcellx for the multiple myeloma cell therapy anito-cel for more than $7 billion in a deal that closed last week. The layoffs are expected to occur by the end of June.
— Lei Lei Wu
💪 Investment firm Banyan BioInnovations debuts:
The firm
said
it will focus on finding best- or first-in-class assets and creating companies to advance them. Banyan is backed by the global life sciences investment bank Locust Walk. The firm is launching with a 50-person team, which includes Locust Walk’s CEO Geoff Meyerson and senior advisor Barbara White.
— Ayisha Sharma
💸 US-China biotech gets $38M:
GSK-partnered LTZ Therapeutics has raised the
funding
, led by GL Ventures, to support its Phase 1 asset LTZ-301 and start a clinical trial for its second asset, called LTZ-232. The four-year-old Redwood City, CA, and Shenzhen biotech has now raised a total of $130 million. It signed a myeloid cell engager
pact with GSK
in November.
— Kyle LaHucik
⏳ Gubra lowers growth guidance, delays obesity trial start:
The company said during its first-quarter
earnings
that it expects CRO revenue to grow by up to 10% this year, down from prior guidance of 5% to 15%. Gubra also confirmed it has submitted a clinical trial application for its obesity candidate UCN2, which was meant to enter Phase 1 development early this year, but had not yet done so.
— Ayisha Sharma