[Translation] A multicenter, randomized, open, positive-controlled study of Y-PEGylated recombinant human growth hormone injection in the treatment of children with short stature
探索益佩生治疗儿童矮小症(特发性矮小症、小于胎龄儿、先天性卵巢发育不良综合征)的药代动力学和药效学的剂量效应关系,为儿童矮小症患者的给药剂量和剂量滴定提供依据。评价益佩生治疗儿童矮小症(特发性矮小症、小于胎龄儿、先天性卵巢发育不良综合征)的安全性耐受性和疗效获益。
[Translation] To explore the dose-response relationship between the pharmacokinetics and pharmacodynamics of Yipeisheng in the treatment of children with short stature (idiopathic short stature, small-for-gestational-age infants, congenital ovarian dysplasia syndrome), and to be administered for children with short stature Dosage and dose titration provide the basis. To evaluate the safety, tolerability, efficacy and benefit of ipeisheng in the treatment of children with short stature (idiopathic short stature, small-for-gestational-age infants, and congenital ovarian dysplasia syndrome).