As in general pathology, digitalization is also inexorably making its way into dermatopathology. This article examines the current state of digitalization in German dermatopathology laboratories based on the authors' own experiences, the current study situation, and a survey of members of the Dermatological Histology Working Group (ADH). Experiences with the establishment of a digital laboratory workflow, artificial intelligence (AI)-based assistance systems, and whole slide images (WSI)-based training programs are discussed. Digitalization in dermatopathology is an opportunity to simplify and accelerate processes, but there are some hurdles to overcome.