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cf. C.A. 51, 18130b.Oats, grown in plots, were fertilized with P₂O₅ containing 2 mc. P³²/g. P₂O₅.The radioactivity was measured with a Geiger counter which moved up and down with constant speed on a carriage which moved on a rail at the plot border.The absorption of P³² from the fertilizer was computed by means of an empirical equation.

European Journal of Medicinal Chemistry

Synthesis of 3-amino-2,3,4,5-tetrahydro-1-benzoxepin-5-ols and their action on gastric motility

Author: Kaupmann, Wilhelm ; Ohlendorf, Heinrich W. ; Wolf, Klaus U.

3-Amino-2,3,4,5-tetrahydro-1-benzoxepin-5-ols, e.g. I (R = H, Me, Et; R¹R²N = MeNH, Me₂N, piperidino) were synthesized by condensation of 2,3,4,5-tetrahydro-1-benzoxepin-3,5-diones with amines and subsequent one or two step reductionThe pharmacol. action of these compounds on the gastric motility of anesthetized rats is described.(±)-Cis-2,3,4,5-tetrahydro-3-(methylamino)-1-benzoxepin-5-ol was selected for further testing.

Blutalkohol

Studies to assess the interaction between alcohol and a new 1,4-benzodiazepine (metaclazepam). 2. Psychophysical performance capability

Author: Mallach, Hans Joachim ; Schenzle, Dieter ; Schmidt, Volker ; Dietz, Klaus

Volunteers were given metaclazepam (I) [84031-17-4] (0-40 mg/kg) with EtOH [64-17-5] (0-1.25 g/kg) in order to determine if any drug-drug interaction exists with regard to psychophys. performance.The large standard deviations in the results make the findings difficult to interpret.However, it seems that the interaction between I and EtOH is additive rather than synergistic or antagonistic.

100 Deals associated with Horizon Immobilien GmbH

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100 Translational Medicine associated with Horizon Immobilien GmbH

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Pipeline

Pipeline Snapshot as of 27 Nov 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

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