A review with 14 references The topics include the history of developing artificial sweeteners replacing traditional natural sweeteners in low-caloric refreshing carbonated beverages, regulatory aspects of artificial sweeteners use in food products, and survey of sweeteners permitted for use (acesulfame K, aspartame, cyclamate, saccharine, sucralose, alitame, neotame, neohesperidine dihydrochalcone, thaumatin protein), and combined use of various sweeteners to optimize beverage flavor and taste.