Delving into the Latest Updates on Amphioxus Cell Technologies, Inc. with Synapse

Overview

Amphioxus Cell Technologies has developed a series of tools for high throughput hepatotoxicity testing.These tools are intended to be used early in the drug discovery process so that structure toxicity relationships can be developed along with SAR, allowing compounds to be optimized for toxicity and activity simultaneously.It became clear that in order for this system to be truly useful, we needed to develop a database of compounds that had been screened through the assays.This would allow our customers to place the results in the context of other known toxins and structurally related compoundsWe set about screening several thousand known compounds in each of seven assays at multiple concentrationsWe quickly realized that our then current information resources were insufficient.We needed a system that could group the results according to chem. structure and that would allow structural searches within the database, yet, we had only rudimentary knowledge of chem. based software.With the help of MDL Information Systems, we were able to implement a relatively sophisticated system quickly and inexpensively without the addition of substantial information technol. resources.

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