A design is described of an equipment that is a modification of a vacuum manifold with five arms that serve as air condensers.A reflux condenser is attached to the top of the manifold.The apparatus can be used for higher boiling solvents with no overflow or drying of any flask.The apparatus is modified to accommodate a large number of reaction vessels.The performance of the apparatus is tested on the solution-phase synthesis of ester amide and guanidine is carries out.The apparatus can be used for the synthesis of analogs with a common chem. and does not require addnl. laboratory space.