Q2 · MEDICINE
Article
Author: Moser, Michael J. ; Germer, J. J. ; Podzorski, Diane S. ; Yao, Joseph D. ; Olivo, Paul D. ; Ledeboer, Nathan A. ; D'Amore, Krista L. ; Johnson, Scott C. ; O'Guin, Andy K. ; Mulligan, Elizabeth K. ; Newman, Andrew C. ; Vaughan, Kimberly A. ; Di Bisceglie, Adrian ; Arens, Max Q. ; Elagin, Slava A.
ABSTRACTA prototype, real-time reverse-transcription PCR assay, based on MultiCode-RTx technology, quantifying hepatitis C virus (HCV) RNA by targeting the HCV 3′ untranslated region demonstrated linearity over 7 logs, with a good correlation between the quantitative results of this assay and the results of two commercially available comparator assays for 466 clinical specimens comprising all six HCV genotypes.