Guangxi Nanning Chemical Pharmaceutical Co. Ltd.

So far, chem. synthesis has gradually replaced seaweed abstraction as a way to manufacture bulk drug mannitol.Chem. synthesis can cause the existence of a small amount of sorbitol in mannitol.This paper gives a full explanation to the cause of formation of sorbitol in mannitol in terms of raw material and production process.

In this paper, chitosan was treated by diatomite, and then granulated by gel method, after crosslinking with epichlorohydrin and amination with diethylenetriamine, molybdate was immobilized on chitosan particles to prepare catalyst particles that had many characteristics, such as acid resistance, high mech. strength and strong adsorption capacity.In the application experiments of preparing mannose from glucose by epimerizationm, the conversion rate of glucose was above 30%, and the effective repeated use rate was above 10 times.

A review.So far the leading technol. to produce food additive-sorbitol liquid is direct hydrogenation of glucose.Sorbitol liquid on the market contains, more or less, a small amount of mannitol.This paper explains in details the cause of formation of mannitol in sorbitol liquid