Institute of Materia Medica, Fourth Military Medical University of the Chinese People's Liberation Army

To explore the safety and efficacy of different doses of genistein capsules in the treatment of postmenopausal osteoporosis and provide a basis for Phase III clinical trials

The pharmacokinetics of genistein capsules after multiple doses in healthy subjects were studied to provide a scientific basis for the formulation of medication regimens for Phase II clinical trials.

The single-dose human pharmacokinetics of genistein capsules in healthy subjects and the pharmacokinetics in the fed state were studied to observe the effect of food on drug absorption, so as to provide a scientific basis for the formulation of the medication plan for Phase II clinical trials and the rational use of drugs in clinical practice.