/ Not yet recruitingPhase 3 一项在复发性多发性骨髓瘤患者中比较卡非佐米联合地塞米松与硼替佐米联合地塞米松的随机、开放标签的3期研究
[Translation] A randomized, open-label, phase 3 study comparing carfilzomib plus dexamethasone with bortezomib plus dexamethasone in patients with relapsed multiple myeloma
主要目的:通过在接受至少1种,但不超过3种既往治疗后发生复发的多发性骨髓瘤(MM)受试者中,比较卡非佐米(Kyprolis;BIW 20/56 mg/m2)联合地塞米松(Kd56)或硼替佐米(万珂)联合地塞米松(Vd)治疗后的无进展生存期(PFS),证实与在复发性或难治性多发性骨髓瘤(RRMM)受试者中开展的全球性ENDEAVOR研究(2011-003)中的趋势的一致性。
[Translation] Primary objective: To confirm consistency with trends seen in the global ENDEAVOR study (2011-003) in subjects with relapsed or refractory multiple myeloma (RRMM) by comparing progression-free survival (PFS) following treatment with carfilzomib (Kyprolis; BIW 20/56 mg/m2) plus dexamethasone (Kd56) or bortezomib (Velcade) plus dexamethasone (Vd) in subjects with relapsed multiple myeloma (MM) after at least 1 but no more than 3 prior therapies.
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