Delving into the Latest Updates on Apollomics (Hong Kong) Limited with Synapse

Overview

Tags

Nervous System Diseases

Congenital Disorders

Hemic and Lymphatic Diseases

Chemical drugs

Disease domain score

A glimpse into the focused therapeutic areas

Technology Platform

Most used technologies in drug development

Targets

Most frequently developed targets

Disease Domain	Count

Hemic and Lymphatic Diseases	1
Nervous System Diseases	1
Neoplasms	1

Top 5 Drug Type	Count

Chemical drugs	1

Top 5 Target	Count

E-sel(Selectin E)	1

本研究的主要目的：描述Uproleselan在中国复发或难治性急性髓系白血病（AML）受试者中的药代动力学（PK）特征；评价Uproleselan联合化疗的安全性和耐受性。次要目的：描述Uproleselan联合化疗所到达的总生存期（OS）；描述Uproleselan联合化疗获得的缓解率（完全缓解[CR]率、CR/完全缓解伴有全血细胞计数不完全恢复[CRi]、CR/完全缓解伴有部分计数恢复[CRh]）；描述Uproleselan联合化疗诱导期重度口腔粘膜炎的发生率及持续时间，巩固期重度口腔粘膜炎的发生率及持续时间。

[Translation]

The primary objectives of this study are: To describe the pharmacokinetic (PK) characteristics of Uproleselan in Chinese subjects with relapsed or refractory acute myeloid leukemia (AML); To evaluate the safety and tolerability of Uproleselan combined with chemotherapy. Secondary objectives: To describe the overall survival (OS) achieved by Uproleselan combined with chemotherapy; To describe the remission rate (complete remission [CR] rate, CR/complete remission with incomplete recovery of complete blood counts [CRi], CR/complete remission with partial recovery of complete blood counts [CRh]) achieved by Uproleselan combined with chemotherapy; To describe the incidence and duration of severe oral mucositis during the induction phase of Uproleselan combined with chemotherapy, and the incidence and duration of severe oral mucositis during the consolidation phase.

Start Date24 Feb 2021

Sponsor / Collaborator

Patheon Manufacturing Services LLC

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100 Clinical Results associated with Apollomics (Hong Kong) Limited

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0 Patents (Medical) associated with Apollomics (Hong Kong) Limited

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100 Deals associated with Apollomics (Hong Kong) Limited

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100 Translational Medicine associated with Apollomics (Hong Kong) Limited

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Pipeline

Pipeline Snapshot as of 23 Dec 2024

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3

Phase 3 Clinical

1

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