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Last update 08 May 2025

Nanjing Zhengda Tianqing Pharmaceutical Co.,Ltd.

Private Company|China|

www.njcttq.com

Private Company|China|

www.njcttq.com

Last update 08 May 2025

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Pipeline

Deal

Translational Medicine

Overview

100 Clinical Results associated with Nanjing Zhengda Tianqing Pharmaceutical Co.,Ltd.

0 Patents (Medical) associated with Nanjing Zhengda Tianqing Pharmaceutical Co.,Ltd.

Literatures (Medical) associated with Nanjing Zhengda Tianqing Pharmaceutical Co.,Ltd.

Shandong Huagong

Synthesis and evaluation of the toxicity of raltitrexed-related impurities to the blood system

Author: Wang, Huaping ; Xu, Dan ; Liao, Qinghong

In this paper, a preparation method of raltitrexed-related impurities was reported, and the effect of related impurities on blood system was studied.The results showed that the method has mild conditions and high yield.The prepared impurities A, B and C are stable quality and can be used to prepare reference materials for the anal. of raltitrexed-related impurities.The effects of impurities A, B and C on blood cells were also studied.The results showed that impurities A, B and C could significantly reduce the number of leukocytes and granulocytes, and their toxicity to the blood system was significantly higher than that of raltitrexed.Therefore, the preparation method of high purity impurities A, B and C can lay a solid foundation for quality research of raltitrexed.

Zhejiang Huagong

Determination of impurity content of 1-hydroxybenzotriazole by high performance liquid chromatography

Author: Lan, Gong-jian ; Xiong, Cai-yun ; Chen, Yu-qing ; Jiang, Jin-xia

Objective: To establish a high performance liquid chromatog. method for the determination of genotoxic impurity 1-hydroxybenzotriazole.Methods: HPLC separation was achieved on a YMC Pack ODS-A column (250 mm×4.6 mm, 5 μm).The mobile phase was 0.1% phosphoric acid-acetonitrile (85:15) at a flow rate of 1.0 mL·min^-1.The detection wavelength was 210 nm and the column temperature was 20°C.Results: The concentration of impurity 1-hydroxybenzotriazole has a good linear relationship with its peak area in the range of 0.05∼1.00 μg·mL^-1.The regression equation was y=80818x-5.7233 (r=0.9999).The lower limit of quantification is 0.05 μg·mL^-1.The average recovery was 90.7% (RSD=7.0%) and 97.8%.Conclusion: The method has high accuracy and good sensitivity, and is suitable for the determination of genotoxic impurity 1-hydroxybenzotriazole.

Anhui Yiyao

Microemulsion system of stanozolol and quality evaluation

Author: Yuan, Hong-qun ; Xiao, Shi-mei ; Li, Pei

The microemulsion delivery system of Stanozolol was prepared and its quality evaluation was established.The microemulsion delivery system was prepared with OP-10 emulsifier, Tween-80 and iso-Pr alc., and its size distribution, Zeta potential and stability were examinedThe contents of Stanozolol were determined by HPLC.The microemulsion of Stanozolol was stable well.The average particle size and Zeta potential were 33.32 nm and 4.35mV, resp.The linear range of Stanozolol was 0.639-3.195 μg (R²=1).The average recovery of Trenbolone Acetate was 99.91% (RSD=0.05%).The preparation technique of the microemulsion is simple and feasible, and its quality is stable and controllable.

100 Deals associated with Nanjing Zhengda Tianqing Pharmaceutical Co.,Ltd.

100 Translational Medicine associated with Nanjing Zhengda Tianqing Pharmaceutical Co.,Ltd.

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Nanjing Zhengda Tianqing Pharmaceutical Co.,Ltd.

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Related

Corporation Tree

Pipeline

Pipeline Snapshot as of 06 May 2026

Deal

Translational Medicine

Profit

Grant & Funding(NIH)

Investment

Financing