Last update 23 Jan 2025

PRAMEF9

Basic Info

Synonyms
PRAME family member 9, PRAMEF9
Introduction
Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex, which mediates ubiquitination of target proteins, leading to their degradation (PubMed:26138980). The CRL2(PRAMEF9) complex mediates ubiquitination and degradation of truncated MSRB1/SEPX1 selenoproteins produced by failed UGA/Sec decoding (PubMed:26138980).

Related

100 Clinical Results associated with PRAMEF9
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100 Translational Medicine associated with PRAMEF9
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0 Patents (Medical) associated with PRAMEF9
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