Last update 08 May 2025

TAS2R4

Basic Info

Synonyms
T2R4, TAS2R4, taste 2 receptor member 4
+ [2]
Introduction
Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. In airway epithelial cells, binding of denatonium increases the intracellular calcium ion concentration and stimulates ciliary beat frequency.

Analysis

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