Last update 21 Mar 2024


Sodium/glucose cotransporter 2

Basic Info

钠葡糖转运子2, Low affinity sodium-glucose cotransporter, Na(+)/glucose cotransporter 2
+ [5]
Electrogenic Na(+)-coupled sugar simporter that actively transports D-glucose at the plasma membrane, with a Na(+) to sugar coupling ratio of 1:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump (PubMed:20980548, PubMed:28592437, PubMed:34880493). Has a primary role in D-glucose reabsorption from glomerular filtrate across the brush border of the early proximal tubules of the kidney (By similarity).


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