Last update 19 Sep 2024

TRPS1

Basic Info

Synonyms
GC79, LGCR, transcriptional repressor GATA binding 1
+ [4]
Introduction
Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.

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