Last update 08 May 2025

SPRY3

Basic Info

Synonyms
HSPRY3, Protein sprouty homolog 3, sprouty RTK signaling antagonist 3
+ [3]
Introduction
Inhibits neurite branching, arbor length and neurite complexity (By similarity). Inhibits EGF-mediated p42/44 ERK signaling (By similarity). Negatively regulates the MAPK cascade, resulting in a reduction of extracellular matrix protein accumulation (PubMed:30878395). May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis (PubMed:9458049).

Analysis

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