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Recent blog posts
uniQure Begins First Patient Treatment in Phase I/II Trial of AMT-162 for SOD1-ALS
Latest Hotspot
3 min read
uniQure Begins First Patient Treatment in Phase I/II Trial of AMT-162 for SOD1-ALS
17 October 2024
uniQure N.V. has announced that the initial participant has received a dose in the Phase I/II clinical study of AMT-162.
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Revolutionizing Antibody Drug Discovery: The Role of AI in Enhancing Design, Optimization, and Affinity Improvement
Bio Sequence
7 min read
Revolutionizing Antibody Drug Discovery: The Role of AI in Enhancing Design, Optimization, and Affinity Improvement
17 October 2024
The application of AI in drug discovery can reduce the development timeline and increase the success rate of new drugs from 12% to 14%.
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Three Gan & Lee Pharmaceuticals Drugs, GZR18, GZR4, and GZR101, Succeed in Phase 2 Trials
Latest Hotspot
4 min read
Three Gan & Lee Pharmaceuticals Drugs, GZR18, GZR4, and GZR101, Succeed in Phase 2 Trials
17 October 2024
Three novel drugs by Gan & Lee Pharmaceuticals-GZR18, GZR4, and GZR101 injections-meet primary goals in Phase 2 trials.
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Check out our latest report
Roche's Bispecific Antibody Drug Emicizumab Patent Research and Practical Operation Guide

Roche's Bispecific Antibody Drug Emicizumab Patent Research and Practical Operation Guide

Emicizumab (Hemlibra) is a bispecific antibody developed by Roche that targets coagulation factors IXa and X. It was first approved by the FDA in November 2017 and received an expanded indication in 2018 for the prophylactic treatment of bleeding in hemophilia A patients, regardless of inhibitor status. This bispecific therapeutic is currently the only bispecific antibody drug used in the field of hemophilia. Since its market launch, Emicizumab has experienced a compound annual growth rate exceeding 300%, with sales surpassing $2 billion by 2020, thus becoming a blockbuster drug. In 2023, Hemlibra reported sales of CHF 4.147 billion (approximately $4.575 billion), reflecting a 16% year-over-year growth. The growth trajectory continues into 2024, with first-half sales reaching CHF 2.143 billion (approximately $2.529 billion). Sales are projected to reach $6.203 billion by 2028. As the highest-grossing bispecific antibody drug currently on the market, Emicizumab's patent landscape garners significant interest. This report aims to guide readers through a step-by-step patent analysis of the Emicizumab drug, ultimately providing a detailed patent landscape map. This can serve as a reference and provide insights for patent strategy in the bispecific antibody field.

GPRC5D Target Patent Research Report

GPRC5D Target Patent Research Report

Multiple myeloma (MM) is a stubborn disease that remains incurable. In recent years, targeted therapies against B-cell maturation antigen (BCMA) have shown promising responses in a substantial number of treated patients. However, the global relapse rate among myeloma patients following anti-BCMA treatment strategies is on the rise. This necessitates continuous exploration of therapies with novel mechanisms of action and new targets, one of which is the G protein-coupled receptor family C group 5 member D (GPRC5D). Due to its unique expression in the plasma cell lineage of MM patients, along with positive data from targeted chimeric antigen receptor T cells (CAR-T) and bispecific antibodies (BsAb), GPRC5D has emerged as an ideal target for anti-myeloma antibodies. The latest "GPRC5D Target Patent Research Report" from Patsnap Lifescience offers an in-depth analysis of global R&D trends related to the GPRC5D target. The report indicates that besides the already marketed Talquetamab, there are 38 drugs currently in clinical or preclinical stages. The R&D trends and market prospects of these drugs are poised to be critical to the future of MM treatment. In terms of patent coverage, the GPRC5D target enjoys a long protection period, providing development companies with prolonged R&D incentives and market exclusivity. The report not only covers the core patent status of approved drugs but also estimates the patent protection periods for clinical stage drugs, offering significant references for R&D decision-making within the industry. Additionally, the report highlights the exploration of combination therapies involving GPRC5D-targeted drugs and their potential applications in other plasma cell disorders, thus providing new perspectives for the future direction of MM treatment. As more companies invest in the development of innovative drugs targeting GPRC5D, we believe this target will offer more treatment options and hope to MM patients.

Global Drug R&D Express (Aug 2024)

Global Drug R&D Express (Aug 2024)

This report compiles and summarizes the basic information of all the first-to-market and special review drugs globally for the month of August totaling 124 drugs. Among them, 1 first-to-market drugs and 1 drugs under special review were selected for detailed analysis. The report provides an in-depth interpretation of these drugs, covering various aspects such as basic information, development status, technological barriers, mechanism of action, clinical trials, and competitive landscape.

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