NeuroTherapia Gets Alzheimer's Association Grant for Alzheimer's Drug Development

27 June 2024
NeuroTherapia, a clinical pharmaceutical company in its early stages, has announced the receipt of a grant from the Alzheimer's Association's Part the Cloud program. This grant is intended to advance the development of NTRX-07, an innovative drug aimed at treating Alzheimer's disease (AD).

NTRX-07 has demonstrated promising results in earlier preclinical studies, as well as in a Phase 1 trial involving a small group of AD patients. This drug targets neuroinflammation, a significant contributor to Alzheimer's disease, and holds the potential to slow down or even halt the disease's progression.

Tony Giordano, CEO of NeuroTherapia, expressed the company's enthusiasm about receiving the grant and the support from Part the Cloud. Giordano emphasized the devastating impact of Alzheimer's disease on millions worldwide and reaffirmed the company's commitment to developing groundbreaking treatments that could significantly improve the lives of patients and their families.

Joseph Foss, M.D., Chief Medical Officer at NeuroTherapia, elaborated on NTRX-07's distinct approach. Unlike traditional treatments, NTRX-07 addresses neuroinflammation that contributes to brain damage in Alzheimer's patients. The drug is administered orally and has shown a favorable safety profile in doses predicted to be effective, based on animal data modeling and recent Phase 1 safety studies conducted with both healthy volunteers and a small cohort of Alzheimer's patients. The upcoming Phase 2a study aims to deepen the understanding of NTRX-07's effects on Alzheimer's patients and may offer early insights into its efficacy.

Heather Snyder, Ph.D., Vice President of Medical and Scientific Relations at the Alzheimer's Association, highlighted the importance of targeting Alzheimer's disease from multiple angles and stages. She emphasized the value of strategic research funding that diversifies the drug development pipeline. The Alzheimer's Association, through Part the Cloud, is excited to support early-stage clinical trials like this one, accelerating the transition of laboratory findings into potential treatments.

This grant marks the second time that the Alzheimer's Association has supported the development of NTRX-07. NeuroTherapia has also secured venture funding from the Alzheimer's Drug Discovery Foundation, Cleveland Clinic, Brain Trust Accelerator Fund II, and Dolby Family Ventures. These investments have enabled the company to complete Phase 1 clinical trials and prepare for the forthcoming Phase 2a trial. This new phase is designed not only to confirm the drug's safety and tolerability but also to provide initial indications of its biological activity.

NeuroTherapia's progress with NTRX-07 represents a significant step forward in the fight against Alzheimer's disease. The support from various organizations underscores the promising potential of this new treatment approach, offering hope for patients and their families affected by this debilitating condition.

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