What are the side effects of Sotrovimab?

12 July 2024
Sotrovimab is a monoclonal antibody treatment that has been authorized for emergency use to treat COVID-19. It is designed to target the spike protein of the SARS-CoV-2 virus, helping to prevent the virus from entering and infecting human cells. While Sotrovimab can be a critical tool in managing COVID-19, it is essential to be aware of the potential side effects associated with its use. Here, we delve into the side effects of Sotrovimab, categorizing them into common, less common, and rare but serious side effects.

Common Side Effects:
One of the most common side effects reported by patients receiving Sotrovimab is infusion-related reactions. These reactions can manifest as fever, chills, or headache during or shortly after the administration of the drug. Other common side effects may include pain, swelling, or redness at the infusion site. These symptoms are generally mild to moderate and tend to resolve on their own without the need for medical intervention.

Less Common Side Effects:
Less common side effects of Sotrovimab may include gastrointestinal symptoms such as nausea, vomiting, or diarrhea. Some patients have also reported experiencing dizziness or lightheadedness. These side effects are usually temporary and may be managed with supportive care and symptom relief measures.

Rare but Serious Side Effects:
Although rare, there are more serious side effects that can occur with the use of Sotrovimab. One such side effect is anaphylaxis, a severe allergic reaction that can be life-threatening. Symptoms of anaphylaxis may include difficulty breathing, swelling of the face and throat, rapid heartbeat, and a drop in blood pressure. Anaphylaxis requires immediate medical attention and intervention.

Another serious side effect is the potential for severe hypersensitivity reactions. These can include skin reactions such as rash, itching, or hives, as well as more systemic symptoms like chest pain, wheezing, or difficulty swallowing. Patients experiencing these symptoms should seek medical care promptly.

Monitoring and Reporting:
Healthcare providers administering Sotrovimab are trained to monitor patients closely during the infusion process and for a period afterward to detect any adverse reactions early. Patients are encouraged to report any side effects they experience to their healthcare provider, even if the symptoms seem mild. This information helps healthcare professionals to manage and mitigate side effects effectively.

Conclusion:
While Sotrovimab has shown promise in treating COVID-19, it is not without its potential side effects. Common side effects are typically mild and manageable, while less common and rare side effects require vigilance and prompt medical attention. Understanding the full spectrum of potential side effects can help patients and healthcare providers make informed decisions about the use of Sotrovimab in the treatment of COVID-19. If you or a loved one is receiving Sotrovimab, it is crucial to maintain open communication with your healthcare provider to ensure any adverse effects are addressed promptly and appropriately.

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