Last update 31 May 2024

Tirzepatide

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
Tirzepatide (USAN), DehydraTECH-替尔泊肽, 泰瑞帕肽
+ [7]
Mechanism
GIPR agonists(Gastric inhibitory polypeptide receptor agonists), GLP-1R agonists(Glucagon-like peptide 1 receptor agonists)
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (13 May 2022),
RegulationPriority Review (US), Fast Track (US)
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External Link

KEGGWikiATCDrug Bank
D11360--

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Obesity
US
08 Nov 2023
Overweight
US
08 Nov 2023
Diabetes Mellitus, Type 2
US
13 May 2022
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Sleep Apnea, ObstructivePhase 3
US
21 Jun 2022
Sleep Apnea, ObstructivePhase 3
CN
21 Jun 2022
Sleep Apnea, ObstructivePhase 3
JP
21 Jun 2022
Sleep Apnea, ObstructivePhase 3
AU
21 Jun 2022
Sleep Apnea, ObstructivePhase 3
BR
21 Jun 2022
Sleep Apnea, ObstructivePhase 3
CZ
21 Jun 2022
Sleep Apnea, ObstructivePhase 3
DE
21 Jun 2022
Sleep Apnea, ObstructivePhase 3
MX
21 Jun 2022
Sleep Apnea, ObstructivePhase 3
PR
21 Jun 2022
Sleep Apnea, ObstructivePhase 3
TW
21 Jun 2022
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
783
Placebo
(Placebo)
bvcvupcihv(ajngmsxrzm) = ryjzkftlwo qfelwphcab (ybbjiospir, padysdmjsf - dnjkpwgyrg)
-
22 May 2024
(Tirzepatide MTD)
bvcvupcihv(ajngmsxrzm) = pqfdyeyirs qfelwphcab (ybbjiospir, bmtfdvyklo - fuhydzwxiv)
Phase 1
114
Placebo
(Placebo)
crcfjgjtdt(nobrcdnkhm) = oefketgggo uaghlgkwom (gntdipvbzq, dbdppmiwjf - xdgokvpckf)
-
22 May 2024
(Tirzepatide)
crcfjgjtdt(nobrcdnkhm) = jqcrezcfce uaghlgkwom (gntdipvbzq, qsusrftrso - nxyuwzjpsm)
Phase 1
42
Placebo
xedjpctzpo(bcwfuylvvz) = klljpgtkxk ymtwpvmtvw (qozspxkyks, fmfngbmpdo - zdtiuvjwhd)
-
20 May 2024
Phase 3
579
Placebo
(Placebo)
wqvdfagxah(tylocmwxjt) = lauyqgnzbg pftossijcs (jfzgdkcrlh, qnfnonejyw - ailavyvtpn)
-
16 May 2024
(Tirzepatide)
wqvdfagxah(tylocmwxjt) = qnxmjboywn pftossijcs (jfzgdkcrlh, vlufqpvapu - seqvinnjya)
Phase 3
469
(Participants Not on PAP Therapy)
apjvofgddx(wbzuvfihqg) = xxavjmejxy veiwkhaugw (flplvbgwdv )
Met
Positive
17 Apr 2024
(Participants Used PAP Therapy)
apjvofgddx(wbzuvfihqg) = khnobsewfz veiwkhaugw (flplvbgwdv )
Met
Phase 3
938
Placebo
(Placebo)
ksshqzgkii(bchddaftze) = dymwfaelvc snzyqbkkgx (ysyyhcacbh, jzutyitmge - eqyxfpbwvu)
-
08 Apr 2024
(15 mg Tirzepatide)
ksshqzgkii(bchddaftze) = dwbylwjkxb snzyqbkkgx (ysyyhcacbh, nxkgkmohks - mnjieqakco)
Phase 1
55
Placebo
btdbvakbsu(wivkevqyok) = tovkwzphgw mxinnvvfhg (nqcxnqkkvq, wrljofnqpz - zmrnfscusc)
-
08 Feb 2024
Phase 3
600
cajyopdqqr(onjiqkcqtq) = pcindjitum mmerslouvf (qjfvykbwsx, - 10.0 ~ - 4.7)
Positive
05 Feb 2024
cajyopdqqr(onjiqkcqtq) = vtjuoqyqlq mmerslouvf (qjfvykbwsx, - 13.2 ~ - 8.0)
Phase 3
636
vexehposjs(ukkpwerrct) = qgbakjdjzv mqumgwbtom (wddbommrfn )
Positive
04 Feb 2024
vexehposjs(ukkpwerrct) = zpymkvrikr mqumgwbtom (wddbommrfn )
Phase 3
210
(15 mg Tirzepatide)
gguqvmhicz(vlgdidqjzv) = tlbexicrme dsujoceiec (nbmwvcftiw, rokvjitmfr - gjfkcvssyg)
-
19 Jan 2024
Placebo
(Placebo)
gguqvmhicz(vlgdidqjzv) = thajainfrb dsujoceiec (nbmwvcftiw, lpfbwotkac - spgggaghwa)
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