What are the top-selling drugs of Perrigo?

20 March 2025
Overview of Perrigo

Company Background
Perrigo Company plc is a global leader in the consumer self-care space with more than a century of experience in delivering quality, affordable over-the-counter (OTC) healthcare products. Originally established as a packager of home remedies in 1887, the company has evolved into a major force in store-brand pharmaceuticals and consumer health solutions. Over the years, Perrigo has transformed its business model by divesting non-core assets and focusing exclusively on consumer self-care, thereby positioning itself as a defensive play in the pharmaceutical landscape. Its business model is unique in that roughly 80% of its revenue is derived from cash sales, making the company particularly resilient during economic downturns. With an extensive portfolio of more than 9,000 SKUs marketed primarily under private-label names in the United States, Europe, Australia, Israel, and other key markets, Perrigo has cemented its reputation for high-quality, affordable care that meets the evolving needs of consumers.

Product Portfolio
Perrigo’s product portfolio is vast and strategically segmented to address multiple facets of consumer healthcare. The company is organized across several major product categories including pain relief, upper respiratory treatments, digestive health, oral care, skin care, women’s health, vitamins/minerals/supplements (VMS), and nutrition. The company’s emphasis on OTC products has allowed it to secure significant market share in categories such as analgesics—the cornerstone of which is its acetaminophen line—as well as cough and cold remedies, infant formulas, and other essential healthcare products. Recent strategic moves, such as regulatory approvals for new self-care offerings and a reshaping of the product mix via targeted divestitures and acquisitions, have bolstered Perrigo’s position as it continues to compete with national brands by replicating their products with store-brand alternatives.

Top-Selling Drugs

Identification of Top Products
Among Perrigo’s extensive portfolio, a few standout products have emerged as clear revenue drivers and bestsellers within its own range. One of the flagship products is the recently FDA-approved Acetaminophen and Ibuprofen Tablets, 250 mg/125 mg. This product is the store-brand OTC equivalent of Advil® Dual Action Tablets and represents a strategic launch that capitalizes on the expiration of marketing exclusivity for the branded version, allowing Perrigo to capture market share in the highly competitive analgesic category.

In addition to this dual-action tablet, Perrigo is known for being the dominant supplier of OTC acetaminophen in the United States. The company’s control over acetaminophen supply is so significant that it reportedly accounts for over half of the U.S. volume in this key pain-relief ingredient, underpinning its role as a primary revenue generator in its pain and sleep-aids collection. This supply dominance is critical because acetaminophen is one of the most widely used pain relievers and fever reducers globally.

Another notable product category includes Perrigo’s broad range of cough and cold remedies—products that have seen heightened demand during pandemic periods due to consumer preference for self-care options over doctor visits. Perrigo’s ability to pivot production to meet surges in demand, particularly for products such as cough syrups and asthma remedies, further reinforces its position as a top-selling drug manufacturer.

Perrigo also leverages its strength as the largest provider of store-brand infant formula and electrolyte liquids, although these products serve a slightly different role in the overall portfolio, they contribute to consistently strong sales figures and help maintain a diversified yet complementary revenue stream alongside the pharmaceuticals.

Sales Performance
The sales performance of Perrigo’s top-selling drugs underscores their market impact. When the Acetaminophen and Ibuprofen Tablets received FDA approval, retail sales for their national brand equivalent – which these OTC tablets mirror – were approximately $69 million in the last twelve months ending January 29, 2023. This figure highlights not only the desirability of the product among consumers seeking effective pain management, but also the financial potential that store-brand equivalents have when positioned against established national brands.

Perrigo’s consistent performance in supplying acetaminophen, which has been in increased demand during the Covid-19 pandemic for both pain and fever management, demonstrates robust sales numbers with the sizeable volume provided. With over half of all U.S. acetaminophen sales attributed to Perrigo’s operations, this product forms a critical pillar of the company’s revenue stream.

Furthermore, gains in market share have been reported across various segments in the Consumer Self-Care business. Financial reports indicate that even though overall sales growth may be tempered by external factors like supply chain disruptions or fluctuations in cough/cold incidence, the strategy to focus on high-volume, store-brand products is proving effective. The consistent organic net sales growth and improved gross margins illustrated in quarterly and annual reports (for example, improvements in adjusted gross margin and EPS metrics) validate that top-selling drugs, particularly in the pain and respiratory categories, deliver strong results for the company.

Market Analysis

Competitive Position
Perrigo’s strategic focus on self-care products places it in a favorable position relative to legacy pharmaceutical companies that are more reliant on prescription drug revenues. In a market where consumers are increasingly favoring OTC options for basic healthcare needs, Perrigo’s extensive portfolio of top-selling drugs like acetaminophen-based analgesics and cough remedies offers a reliable competitive edge. Analysts have even classified Perrigo as a defensive play in the pharmaceutical market; its products—including its dominant acetaminophen supply—tend to maintain stable demand even during economic downturns due to their status as essential healthcare items.

Perrigo’s leading market share in key OTC categories shields it from many of the risks that impact prescription drug manufacturers, such as reimbursement challenges or rapidly shifting regulatory landscapes. The company’s robust production and distribution networks—built on decades of experience in fast-moving consumer goods—ensure that these top-selling drugs are widely available and competitively priced.

Moreover, the company’s transformation strategy—divesting non-core assets such as its RX businesses and investing in self-care initiatives—has enhanced its focus on high-volume, high-demand drug categories. This streamlining not only sharpens its competitive edge but also allows Perrigo to respond rapidly to market changes. The defensive nature of its OTC products, which cover everything from pain relief to upper respiratory treatments, means that its top sellers are less susceptible to the pricing pressures and patent litigations that commonly affect prescription drugs.

Market Trends
Several current market trends are favorable to Perrigo’s top-selling drugs. The shift of consumer preference from prescription-based treatments to self-care remedies has accelerated, driven by increasing healthcare costs and a desire for convenience. With the Covid-19 pandemic reinforcing the need for home-based treatment options, the demand for drugs that address fundamental needs—such as pain management (acetaminophen/ibuprofen combinations) and respiratory relief—has surged.

Additionally, regulatory environments have been increasingly facilitating the switch of products from prescription-only to OTC status. Perrigo has successfully leveraged this trend, as evidenced by the recent FDA approval of products like its dual-action acetaminophen and ibuprofen tablets that provide a store-brand alternative to national brands like Advil Dual Action Tablets. This regulatory landscape helps expand the market for Perrigo’s high-selling drugs, as consumers gain easier access to trusted analgesic and cough remedies without the cost or hassle of prescription requirements.

Furthermore, the cost-conscious nature of modern consumers is driving increased demand for value-driven store-brand products. Perrigo’s ability to offer quality, affordable alternatives that deliver comparable efficacy to national brands continues to resonate strongly with consumers, thereby supporting the strong sales performance of its top-selling drugs. This trend is particularly evident in the analgesic category, where the widespread use and over-the-counter availability of acetaminophen and ibuprofen have historically anchored high sales volumes.

Future Prospects

Pipeline Products
Looking ahead, Perrigo is not resting on its laurels. The company’s future product pipeline is designed to support and expand on the success of its top-selling drugs. New product introductions such as the OTC version of Nasonex®—which involves a licensing agreement to switch a prescription nasal spray to an OTC self-care product—demonstrate the company’s operational capability to move innovative treatments across the regulatory spectrum. These kinds of Rx-to-OTC switches, along with the development of additional therapeutic equivalents such as its FDA-approved dual-action pain relief tablets, are expected to reinforce the company’s position in the self-care sphere by broadening the product portfolio and tapping into higher growth segments.

Perrigo’s emphasis on innovation is also evident in its investments in research and development, particularly in enhancing its supply chain and production capabilities to support the consistent manufacturing of top-selling drugs. This R&D focus not only supports current high-volume drugs such as acetaminophen formulations but also paves the way for the introduction of new categories such as OTC products for women’s health and next-generation respiratory therapies.

Strategic Initiatives
Strategic initiatives are at the heart of Perrigo’s future growth prospects. The company has embarked on several key strategic moves that are expected to fortify its market leadership in store-brand OTC products:

1. Portfolio Reconfiguration and Divestitures:
Perrigo has methodically divested non-core businesses and focused its resources on consumer self-care. For instance, the divestiture of its generic prescription business and certain non-core international assets has allowed the company to hone its focus on products with high market penetration and strong consumer demand such as its acetaminophen and ibuprofen formulations.

2. Regulatory Approvals and Market Expansion:
The company is leveraging regulatory milestones, such as the FDA approval for its dual-action Acetaminophen and Ibuprofen Tablets, to capture new market opportunities and drive volume growth. This approval not only validates the product’s equivalence to well-known national brands but also opens avenues to expand into new retail channels and increase market penetration in critical regions.

3. Supply Chain Enhancements and Production Efficiency:
Continuous investments in supply chain reinvention, including increased manufacturing capacity and strategic pricing initiatives, support the consistent production and distribution of top-selling drugs. Improvements in these areas lead to better gross margins and lower operating costs, thus ensuring that high-demand products maintain strong sales performance even in a competitive environment.

4. Expansion Through Acquisitions:
Strategic bolt-on acquisitions, as seen with Perrigo’s acquisition of Eastern European OTC brands, broaden the product portfolio and extend reach in key markets like skin care and personal wellness. These initiatives complement the strong performance of top-selling drugs by diversifying revenue sources and mitigating risks across regional markets.

5. Innovation in Product Development:
The company continues to invest in R&D to optimize its existing products and bring innovative new formulations to market. The focus on developing OTC equivalents with enhanced efficacy and safety profiles, along with efforts to rapidly switch promising prescription drugs to the OTC category, defines Perrigo’s forward-looking approach. This strategy ensures that even as market dynamics and consumer preferences evolve, the company’s portfolio of top sellers remains both relevant and profitable.

Conclusion
In summary, Perrigo’s top-selling drugs are anchored by its leadership in the pain and respiratory categories, with the Acetaminophen and Ibuprofen Tablets (250 mg/125 mg) serving as a recent flagship product following FDA approval. This product, designed as a store-brand equivalent to Advil® Dual Action Tablets, is emblematic of Perrigo’s broader strategy to deliver high-quality, affordable alternatives to national brands—a strategy that has also enabled the company to supply over half of the U.S. acetaminophen volume.

From the fundamental aspects of its company background and extensive product portfolio, Perrigo has consistently focused on delivering essential self-care products that respond to both consumer needs and market trends. Its dominant position in highly competitive OTC segments, reinforced by robust sales performance figures, positions its top-selling drugs as critical revenue drivers. The firm’s defensive market positioning, based on cash sales and consumer reliance on inexpensive, high-quality alternatives, affords it a competitive advantage that is further enhanced by strategic initiatives—ranging from regulatory approvals and innovative product development to targeted divestitures and supply chain investments.

Moreover, market trends such as the shift toward OTC self-care, regulatory moves facilitating prescription-to-OTC switches, and the cost-conscious behavior of modern consumers all align favorably with Perrigo’s strengths. Looking to the future, the company’s strong pipeline—bolstered by additional product approvals and strategic acquisitions—coupled with ongoing operational improvements, signals sustained growth for its top-selling drugs. With comprehensive strategic initiatives focused on portfolio reconfiguration, supply chain optimization, and innovation, Perrigo is well positioned to maintain and enhance its leadership in the self-care market.

Ultimately, the detailed analysis of Perrigo’s business model, competitive position, and strategic directions confirms that its top-selling drugs—especially in the pain and respiratory categories—will continue to serve as key growth drivers, ensuring that the company maintains a robust market share while adapting to new opportunities. The explicit focus on defensive, high-demand products not only secures current success but also lays a solid foundation for future expansion in the dynamically evolving global self-care marketplace.

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