FAKHRAVAC, developed in response to the
COVID-19 pandemic, stands as a significant milestone in the global effort to combat the virus. This vaccine, targeted at preventing COVID-19, represents a collaborative effort among Iranian research institutions, spearheaded by the knowledge-based company Shifafarmed. The vaccine is named in honor of Mohsen Fakhrizadeh, a prominent Iranian scientist. FAKHRAVAC is an inactivated virus vaccine, which means it uses a killed version of the
SARS-CoV-2 virus to stimulate an immune response without causing the disease.
The development of FAKHRAVAC has undergone rigorous phases, beginning with preclinical trials and moving into several phases of human clinical trials. These trials aim to determine the vaccine's safety, efficacy, and potential side effects. Early data from these trials indicated that FAKHRAVAC could induce a robust immune response against the SARS-CoV-2 virus, paving the way for emergency use authorization in Iran. As of now, the vaccine is a part of Iran's national vaccination campaign and is contributing to the country's efforts to achieve herd immunity.
FAKHRAVAC's mechanism of action is rooted in its use of an inactivated form of the SARS-CoV-2 virus. Inactivated vaccines have a long history of use against various infectious diseases, including
influenza and
polio. The process involves growing the virus in a controlled environment, followed by a chemical treatment that kills the virus, rendering it incapable of causing disease. However, despite being inactivated, the virus retains its structural integrity, particularly the spike protein, which is crucial for eliciting an immune response.
When FAKHRAVAC is administered, the immune system recognizes the inactivated virus as a foreign invader. This recognition triggers the production of antibodies specifically targeting the spike protein of SARS-CoV-2. Additionally, the vaccine stimulates the development of memory cells. These memory cells remain in the body and can mount a rapid and effective response if the person is later exposed to the live virus. This dual action of antibody production and memory cell development is essential for providing both immediate and long-term protection against COVID-19.
The primary indication for FAKHRAVAC is the prevention of COVID-19. COVID-19, caused by the SARS-CoV-2 virus, is a
respiratory illness with a wide range of symptoms, from mild
respiratory issues to severe, life-threatening conditions such as
acute respiratory distress syndrome (ARDS). The virus primarily spreads through respiratory droplets when an infected person coughs, sneezes, or talks, making vaccination a key strategy in controlling its spread.
FAKHRAVAC is designed to be administered in a series of doses, with a specific schedule that has been optimized based on clinical trial data. The vaccine is indicated for use in adults, and ongoing studies are evaluating its safety and efficacy in younger populations. The goal of vaccination with FAKHRAVAC is not only to reduce the incidence of COVID-19 but also to decrease the severity of the disease in breakthrough cases, ultimately reducing hospitalizations and deaths.
Given the global nature of the COVID-19 pandemic, FAKHRAVAC's development and deployment are part of a larger, worldwide effort to achieve effective control of the virus. While many vaccines have been developed and distributed globally, each one, including FAKHRAVAC, adds to the collective arsenal against this unprecedented public health challenge. By contributing to the global vaccination campaign, FAKHRAVAC plays a vital role in the fight against COVID-19, offering hope for a return to normalcy and the prevention of future outbreaks.
In conclusion, FAKHRAVAC embodies the scientific community's rapid response to a global crisis. Through a combination of traditional vaccine technology and rigorous clinical testing, it provides a valuable tool in the ongoing battle against COVID-19. As vaccination efforts continue worldwide, FAKHRAVAC stands as a testament to the power of innovation and international collaboration in addressing one of the most significant health challenges of our time.
How to obtain the latest development progress of all drugs?
In the Synapse database, you can stay updated on the latest research and development advances of all drugs. This service is accessible anytime and anywhere, with updates available daily or weekly. Use the "Set Alert" function to stay informed. Click on the image below to embark on a brand new journey of drug discovery!


