Zura Bio Limited, a Nasdaq-listed clinical-stage immunology company, announced its first quarter financial results for 2024, alongside recent business developments. The company, which focuses on developing innovative dual-pathway antibodies for autoimmune and inflammatory diseases, has reported significant milestones that bolster its future prospects.
During the first quarter of 2024, Zura Bio successfully raised $112.5 million through an oversubscribed private placement. This funding, sourced from both new and existing life sciences institutional investors, is projected to support the company’s operational needs until 2027. As of March 31, 2024, the company had $89.8 million in cash, down from $99.8 million at the end of 2023.
The company has also made strategic leadership changes. In April 2024, Robert Lisicki was appointed as the new Chief Executive Officer, stepping in for founding CEO Someit Sidhu, M.D., who remains on the board. Additionally, in January 2024, Dr. Kiran Nistala was named Executive Vice President of Development and Chief Medical Officer.
Zura Bio’s development pipeline is progressing as scheduled, with plans to initiate Phase 2 studies for
tibulizumab (ZB-106) for
systemic sclerosis (SSc) by the fourth quarter of 2024 and for
hidradenitis suppurativa (HS) by the second quarter of 2025. This dual-pathway antibody targets
IL-17 and
BAFF, potentially offering significant benefits to patients suffering from these underserved conditions.
Financially, the company's R&D expenses for Q1 2024 were $3.6 million, a decrease from the $4.9 million spent in the same period in 2023. This reduction is largely attributed to a decrease in share-based compensation linked to license agreements. Conversely, there was an increase in personnel compensation and costs related to consulting services and product manufacturing.
General and administrative expenses saw a rise, amounting to $4.8 million for the first quarter of 2024, up from $2.8 million in the same quarter of the previous year. This increase was driven primarily by higher personnel costs, including share-based compensation, and an uptick in professional services expenses.
The net loss for the first quarter of 2024 was reported at $7.7 million, showing improvement from the $9.6 million net loss recorded in the first quarter of 2023.
Looking ahead, Zura Bio is actively monitoring the progress of its other pipeline candidates. For
ZB-168, the company is closely watching Phase 2
IL-7R external catalysts in conditions such as
ulcerative colitis,
atopic dermatitis, and
alopecia areata. Similarly, for
torudokimab (ZB-880), Phase 2 and Phase 3
IL-33 external catalysts in
asthma and
chronic obstructive pulmonary disease are being tracked.
Zura Bio aims to advance its portfolio of therapies through rigorous clinical development, with three assets ready for Phase 2 trials following successful Phase 1/1b studies. The company is committed to addressing unmet medical needs in the autoimmune and inflammatory disease space.
With robust financial backing and a clear strategic direction, Zura Bio is well-positioned to continue its mission of bringing novel therapies to market, ultimately improving the lives of patients with complex immune-mediated conditions.
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