Bio Sequence

Biological Glossary | What is Intron?

8 November 2023
2 min read

An intron, derived from the term "intragenic region", is a nucleotide sequence within a gene that does not directly code for proteins and does not remain in the final mature mRNA molecule following the gene's transcription. Instead, these segments are removed during the pre-mRNA stage of mRNA maturation by a process called RNA splicing. Introns come in four distinct types: tRNA introns, group I introns, group II introns, and spliceosomal introns. They are seen in the genes of most organisms and viruses and can be found in both protein-coding genes and noncoding genes. Precise removal of introns is critical as any leftover intron nucleotides or exon nucleotide deletions can result in a faulty protein, potentially leading to a frameshift where the genetic code is read incorrectly.

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