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Last update 23 Jan 2025

Tooth Resorption

Last update 23 Jan 2025

Basic Info

Synonyms

Pathological resorption of teeth, Pathological resorption of tooth, Pathological resorption of tooth (disorder)

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Introduction

Resorption of calcified dental tissue, involving demineralization due to reversal of the cation exchange and lacunar resorption by osteoclasts. There are two types: external (as a result of tooth pathology) and internal (apparently initiated by a peculiar inflammatory hyperplasia of the pulp). (From Jablonski, Dictionary of Dentistry, 1992, p676)

Clinical Trials associated with Tooth Resorption

CTRI/2024/07/070145

/ Not yet recruitingNot ApplicableIIT

Correlation Analysis of Interleukin-1a Levels in Gingival Crevicular Fluid with the Occurrence of External Root Resorption in Patients with Traumatic Dental Injury: A Prospective cohort Study - NIL

Start Date01 Aug 2024

Sponsor / Collaborator-

RBR-8m8754y

/ Not yet recruitingNot ApplicableIIT

Evaluation of the sucess rate of two antibiotic pastes used in lesion sterilization and tissue repair: a randomized clinical study

Start Date01 Aug 2024

Sponsor / Collaborator-

NCT06567730

/ Not yet recruitingNot ApplicableIIT

Comprehensive Comparison of Canine Retraction Using Nickel-titanium Closed-coil Springs Versus Elastomeric Power Chains During Orthodontic Treatment - A Split-mouth Randomized Controlled

The objective of this study is to compare the canine retraction rate (in mm with a 100 mm marked scale) using Ni-Ti closed-coil springs versus elastomeric power chains during canine retraction in subjects with first premolar extractions over a period of three months.
After the extraction of all first premolars under local anesthesia. For canine retraction, Ni-Ti closed-coil springs and elastomeric power chains will be randomly allocated to the right and left quadrants of both arches.
Radiographic measurement (root resorption) and clinical measurements (canine retraction, plaque accumulation and gingival health) will be recorded at four points in time. First, at the start of the canine retraction (T0), after first month (T1), second month (T2) and third month follow-up (T3).

Start Date01 Aug 2024

Sponsor / Collaborator

AGA Khan University Hospital

100 Clinical Results associated with Tooth Resorption

100 Translational Medicine associated with Tooth Resorption

0 Patents (Medical) associated with Tooth Resorption

888

Literatures (Medical) associated with Tooth Resorption

01 Feb 2025·Orthodontics & Craniofacial Research

Preventive and reparative effects of low‐level laser therapy on orthodontically induced inflammatory root resorption—An animal study

Article

Author: Yang, Kai ; Du, Rina ; Bai, Linna ; Xu, Bowen

AbstractBackgroundOrthodontically induced inflammatory root resorption (OIIRR) is one of the most important side effects of orthodontic treatment. Low‐level laser therapy (LLLT) is a useful way to reduce the orthodontic treatment duration and may have some effect on preventing and repairing OIIRR. However, the specific effects of LLLT on OIIRR remain unknown.ObjectiveOur research aimed to evaluate the Dentin Sialophosphoprotein (DSPP) expression level and root resorption volume during treatment and retention to explore the role of LLLT in preventing and repairing OIIRR.MethodsThirty‐seven 6‐week‐old male Sprague–Dawley rats were selected to establish an OIIRR model; the rats were divided into Group B (blank), Group F (force), Group F(LLLT) (force and LLLT), Group F+R (force and retention) and Group F+R(LLLT) (force, retention and LLLT). The root resorption volume of the distal buccal root and mesial root in the maxillary left first molar was calculated by micro‐CT, and the DSPP expression level on the compression side of the periodontal ligament was analysed by immunohistochemical staining.ResultsThe resorption volume in Group F was greater than that in Group F(LLLT). For the mesial root, the volume in Group F was greater than that in Groups F+R and F+R(LLLT). For the distal buccal root, the volume in Groups F and F+R was greater than that in Group F+R(LLLT). The DSPP level in Group F(LLLT) was greater than that in Group F and there was no difference between Groups F+R and F+R(LLLT).ConclusionsLLLT has a certain preventive effect and a limited reparative effect on OIIRR in rats.

01 Jan 2025·Clinical Case Reports

Managing Large Perforated Internal Root Resorption With Partial Pulpectomy: A Case Report

Article

Author: Asgary, Saeed

ABSTRACTInternal root resorption (IRR) is a complex and often asymptomatic dental condition that can severely compromise tooth vitality and function. This case report presents the successful management of a perforated large IRR lesion in a 49‐year‐old female using an ultraconservative approach involving partial pulpectomy (PP) using calcium‐enriched mixture (CEM) cement. The patient, initially presenting with an asymptomatic resorptive lesion in her left first premolar, underwent ultraconservative PP following diagnosis via conventional radiography and cone beam computed tomography. Despite encountering excessive bleeding during treatment, the tampon technique using CEM cement allowed reasonable hemostasis and effective sealing of the pulp stump, facilitating the preservation of tooth structure. Follow‐up at 2 weeks and 2 years showed positive outcomes, including cessation of the resorptive process and normal periodontal health. This case demonstrates the efficacy of vital pulp therapy, specifically partial pulpectomy, in managing advanced IRR and underscores the potential for tooth preservation and long‐term stability through an ultraconservative approach.

01 Dec 2024·Orthodontics & Craniofacial Research

Effects of isotretinoin on tooth movement, orthodontically induced and non‐orthodontic root resorption: A micro‐CT study

Article

Author: Keles, Ali ; Halicioglu, Koray ; Kaya, Ozlem Tugce Cilingir ; Kayali, Damla ; Gok, Gulay Dumanli ; Olgac, Nejat Vakur

AbstractObjectivesThis study aims to investigate whether cumulative dose‐dependent isotretinoin (Roaccutane®) could affect orthodontic tooth movement (OTM) and root resorption.Materials and MethodsNinety male Wistar Albino rats were divided into 4 groups. While, the control (SALINE), solvent (SOYBEAN) and orthodontic drug (ISOTM) groups underwent orthodontic force, the non‐orthodontic drug group (ISO) did not. The rats were administrated saline, soybean oil (SBO) and isotretinoin diluted in SBO (ISOTM, ISO) for 30 days, respectively. Six rats were euthanized in each orthodontic group. Fifty grams of orthodontic force was applied to the remaining rats' first molars using the incisors as anchorage. Six more rats in each group were euthanized on the 7th, 14th and 21st days of the force application. In the ISO group, six rats were euthanized on the 37th, 44th and 51st days of administration. Six rats that were euthanized for ISOTM on the 30th day were also used for ISO to reduce the number of rats used. Micro‐computed tomography (micro‐CT) and histological analysis were performed.ResultsIndependent of orthodontic force, isotretinoin caused root resorption in the apical region. However, there was no statistically significant influence of isotretinoin on OTM and orthodontically induced root resorption (OIRR).ConclusionsDespite the lack of strong evidence supporting the orthodontically induced resorptive effect of isotretinoin, this study provided findings regarding the resorptive effects of isotretinoin on non‐orthodontic root resorption. Therefore, the present results underscore the importance of close monitoring during orthodontic treatment to mitigate potential root resorption in patients who use isotretinoin because of acne complaints.

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Tooth Resorption

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