Mucinosis, Follicular

Last update 23 Jan 2025

Basic Info

Synonyms

Alopecia Mucinosa, Alopecia Mucinosis, Alopecia mucinosa

+ [24]

Introduction

A disease of the pilosebaceous unit, presenting clinically as grouped follicular papules or plaques with associated hair loss. It is caused by mucinous infiltration of tissues, and usually involving the scalp, face, and neck. It may be primary (idiopathic) or secondary to mycosis fungoides or reticulosis.

Clinical Trials associated with Mucinosis, Follicular

IRCT20211210053344N1

/ SuspendedPhase 2/3IIT

Evaluation of efficacy and safety of electrosurgery in comparison with cryosurgery in patients with sebaceous hyperplasia, seborrheic keratosis, cherry angioma and skin tag: A controlled randomized clinical trial

Start Date21 Jan 2022

Sponsor / Collaborator

Iran University of Medical Sciences & Health Services

100 Clinical Results associated with Mucinosis, Follicular

100 Translational Medicine associated with Mucinosis, Follicular

0 Patents (Medical) associated with Mucinosis, Follicular

462

Literatures (Medical) associated with Mucinosis, Follicular

01 Feb 2025·Journal of Cutaneous Pathology

Histopathologic Comparisons of Discoid Lupus Erythematosus and Folliculotropic Mycosis Fungoides in a Series of 43 Cases

Article

Author: Sundram, Uma ; Cascardo, Camilla A. ; Oska, Sandra ; Mansour, Meghan R.

ABSTRACTBackgroundFolliculotropic mycosis fungoides (FMF) is a rare cutaneous malignancy that can be mistaken for inflammatory diseases, such as discoid lupus erythematosus (DLE), due to the variability of histopathological findings.MethodsThis study aims to provide dermatopathologists with evidence‐based histopathologic criteria to distinguish DLE from FMF by reporting overlapping and distinguishing microscopic features. Forty‐three biopsies from patients with a confirmed diagnosis of DLE or FMF were graded for the presence or absence of 18 histopathologic features.ResultsThe main histopathologic findings present in nearly all DLE and FMF biopsies were folliculocentric and folliculotropic patterns. Comedones, granulomas, and folliculitis were not prominent. Follicular hyperplasia, follicular plugging, interstitial mucin, lichenoid/interface dermatitis, and plasma cells were significantly more common in DLE biopsies, while follicular mucinosis and eosinophils were significantly more common in FMF samples. Cytologic atypia ranged from none to mild in DLE and mild to moderate in FMF. Rarely, both sets of biopsies contained epidermotropism, spongiosis, or peri‐eccrine infiltration.ConclusionWhile many histopathological features present in DLE overlap with features found in FMF, such as folliculocentrism and folliculotropism, significant differences do exist. Therefore, when diagnosing FMF, it is important to follow established criteria that differentiate this malignancy from inflammatory conditions such as DLE.

01 Dec 2024·Annales de Dermatologie et de Vénéréologie

Unilesional folliculotropic mycosis fungoides associated with follicular mucinosis in children: 2 cases and literature review

Article

Author: Lasek-Duriez, A ; Pollyn-Millot, C ; Quinchon, J-F ; Modiano, P

01 Dec 2024·Dermatologic Surgery

Utilization of Injectable and Device-Based Treatments in Medical Dermatology: A Survey on Demographics, Conditions, and Resident Involvement

Article

Author: Almukhtar, Rawaa ; Fathizadeh, Sam ; Richmond, Alexandra

BACKGROUNDInjectable and device-based treatments are used for medical dermatologic conditions, but understanding dermatologists' practices remains limited.OBJECTIVEThis study examines injectable and device-based treatments for medical dermatologic conditions to identify patterns and potential improvements.MATERIALS AND METHODSA survey was distributed to Association of Academic Cosmetic Dermatology members, covering practice settings, conditions treated, pricing, and resident involvement.RESULTSThirty-four of 40 (85%) respondents practiced in academic teaching hospitals, primarily in urban settings. Conditions treated included acne vulgaris, alopecia, skin cancers, disorders of pigmentation, follicular disorders, gender-affirming care, birthmarks, oncodermatology, rosacea, scars, tattoos, and vascular lesions. Treatments were offered at various prices, with clinical trials and insurance used in some cases. Resident involvement ranged from 72% to 94% of cases. Respondents also reported laser usage, with 100% using lasers for treating scars, 98% for treating vascular lesions, 98% for treating rosacea, and 88% for treating disorders of pigmentation. For acne vulgaris and associated scarring, the top treatments were chemical peels (86%), lasers (83%), and mechanical modalities (48%). With gender-affirming care, respondents used lasers (100%), filler (55%), and neurotoxins (48%).CONCLUSIONAcademic dermatologists treat medical dermatologic conditions and involve residents.

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