Atrioventricular Septal Defect

MONDAY, March 27, 2023 (American Heart Association News) -- Cynthia Felix Jeffers was a baby when her 12-day-old sister died from a congenital heart defect. She was 22 when her brother, a week shy of 20, died from the same condition. Cynthia, meanwhile, grew up in New York City being told there was nothing wrong with her heart. Doctors insisted her shortness of breath was caused by asthma. Even though inhalers provided no relief, tests showed her heart was fine. At 27, she had a son. Elijah was nearly 1 when his pediatrician detected a heart murmur. Further testing revealed he was born with a version of the same problem that claimed the lives of her siblings. Elijah had a hole in the center of his heart called an incomplete atrioventricular septal defect, or AVSD. The problem can affect circulation. "It felt like a death sentence," Cynthia said. It wasn't, though, because of a crucial difference in the diagnosis. Her sister and brother had "complete" defects that affected all four chambers. Elijah's defect was incomplete. Doctors fixed his problem through a minimally invasive heart surgery that left only a tiny scar. Within a week, he was up and about. All the while, she still found herself short of breath. At times, she could barely walk to the end of the street, let alone climb stairs. On several occasions, she passed out. Sometimes her fingers turned blue. "A lot of things were happening that didn't make sense," she said. Ultimately, she made an appointment with a cardiologist who specializes in adults with congenital heart defects. He determined that Cynthia – just like Elijah – had an incomplete AVSD. "I was shocked but also felt a sense of relief, because I knew I wasn't crazy," she said. "The doctors had dismissed me and my symptoms for so long that I had begun to doubt myself." About 10 years after Elijah's surgery, a congenital cardiac surgeon performed the same minimally invasive heart surgery on Cynthia. Unlike her son, she didn't have an easy recovery. She had very little energy. She twice had to have fluid drained from her lungs. When insurance denied cardiac rehab, Cynthia started riding her exercise bike and taking walks around the neighborhood with her husband, Edwin. Within a year, she noticed a big difference in her stamina. Two years later, she could walk for hours without feeling fatigue. "I could walk my son to school without stopping to rest," she said. "That was big for me." Years later, Cynthia's heart rate began to spike as high as 250 to 270 beats per minute. She passed out several times, once landing so hard that she broke her collarbone, another time breaking a thumb. She was diagnosed with supraventricular tachycardia, a condition that causes a rapid or chaotic heartbeat. She underwent several ablation procedures to essentially destroy the electrical pathways that caused the irregular heartbeat. The arrhythmia may have been caused by the scarring in her heart from her heart surgery, said Dr. Adam Small, the cardiologist specializing in adults with congenital heart defects who treated Cynthia. "When the electricity encounters a scar, its course gets diverted, and that can be the birth of an arrhythmia, where the electrical system sort of goes haywire because it's trying to navigate around or through scars," he said. For now, Small and his colleagues manage Cynthia's condition with medication. They also monitor her heart rate with an implantable loop recorder, a thumb drive-sized device that sits under the skin. She also has an echocardiogram twice a year to monitor her tricuspid valve, which doesn't close property. As a result, blood leaks back into her heart's right upper chamber. Cynthia wonders how things might be different if she had been diagnosed as a child. She points to Elijah, who is now 25, a healthy and athletic physical education teacher. "He hasn't let it limit him in any way, and I attribute that to the fact that we caught it very early," she said. Determined to raise awareness about congenital heart defects, Cynthia became involved with the American Heart Association. She has done several Heart Walks and participated in the organization's Go Red for Women campaign, sharing her story and hosting events for Hispanic women. Her message: "As caregivers, us women often put ourselves last and ignore the pain, and a lot of us in the Hispanic community dismiss things. Through education and advocacy, we can save lives." After her heart surgery, Cynthia got a tattoo on her upper back. One side has an image of the squiggly lines from her electrocardiogram. The other side shows Elijah's EKG reading. Those drawings are bridged by the word "faith." "The connection between us is very meaningful," she said. "We both survived this together and came out stronger because of it." American Heart Association News covers heart and brain health. Not all views expressed in this story reflect the official position of the American Heart Association. Copyright is owned or held by the American Heart Association, Inc., and all rights are reserved. By Tate Gunnerson, American Heart Association News Posted March 2023

DUBLIN, Oct. 4, 2022 /PRNewswire/ -- The "Pediatric Interventional Cardiology Market: Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2022-2027" report has been added to ResearchAndMarkets.com's offering. The global pediatric interventional cardiology market reached a value of US$ 2.28 billion in 2021. Looking forward, the market is projected to reach a value of US$ 3.46 billion by 2027, exhibiting a CAGR of 6.80% during 2022-2027. Keeping in mind the uncertainties of COVID-19, the analyst is continuously tracking and evaluating the direct as well as the indirect influence of the pandemic. These insights are included in the report as a major market contributor. Pediatric interventional cardiology is a subset of cardiology that involves the use of specific catheter-based techniques to treat heart disorders in infants, children, and adolescents up to 18 years of age. They include balloon angioplasty, coil occlusion, stent implantation, and aortic valve stenosis. As compared to conventional cardiological treatments, pediatric interventional cardiology is more minimally invasive, thus reducing post-surgery complications. Consequently, they are extensively employed for performing angioplasty, valvuloplasty, coronary thrombectomy, and congenital heart defect correction procedures across clinical testing laboratories, hospitals, cardiac centers, and research institutes. The increasing instances of various congenital cardiac diseases in children, such as atrial septal defect (ASD), atrioventricular canal defect, patent ductus arteriosus (PDA), and ventricular septal defect (VSD) represent one of the key factors driving the pediatric interventional cardiology market growth. The introduction of novel and more efficient pediatric interventional cardiology devices, including catheters, bio-absorbable stents, guidewires, balloons, stents, vascular closure devices, atherectomy devices is acting as another major growth-inducing factor. In line with this, the shifting inclination of patients toward non-invasive medical treatment procedures, along with the rising awareness regarding the associated benefits, such as lower risk of infection, shorter postoperative recovery times, and avoidance of large scars is also driving the market growth. Other factors, including rising healthcare expenditure and the numerous initiatives being undertaken by governments of various nations to speed-up regulatory procedures, are creating a positive outlook for the market. The market is also driven by extensive research and development (R&D) activities, increasing consumer healthcare expenditure and investments by governments and non-government organizations (NGOs) for strengthening the existing healthcare infrastructure, and significant technological advancements in the field of cardiology. Competitive Landscape The competitive landscape of the industry has also been examined along with the profiles of the key players being Biotronik SE & Co. KG, Boston Scientific Corporation, Cardinal Health Inc., Edwards Lifesciences Corporation, General Electric Company, Koninklijke Philips N.V., Lepu Medical Technology (Beijing) Co. Ltd., Medtronic plc, NuMED Inc., Siemens Healthineers AG, Terumo Corporation and W. L. Gore & Associates Inc. Key Questions Answered in This Report How has the global pediatric interventional cardiology market performed so far and how will it perform in the coming years? What has been the impact of COVID-19 on the global pediatric interventional cardiology market? What are the key regional markets? What is the breakup of the market based on the device type? What is the breakup of the market based on the procedure? What is the breakup of the market based on the End-use? What are the various stages in the value chain of the industry? What are the key driving factors and challenges in the industry? What is the structure of the global pediatric interventional cardiology market and who are the key players? What is the degree of competition in the industry? Key Topics Covered: 1 Preface 2 Scope and Methodology 3 Executive Summary 4 Introduction 4.1 Overview 4.2 Key Industry Trends 5 Global Pediatric Interventional Cardiology Market 5.1 Market Overview 5.2 Market Performance 5.3 Impact of COVID-19 5.4 Market Forecast 6 Market Breakup by Device Type 6.1 Closure Devices 6.1.1 Market Trends 6.1.2 Market Forecast 6.2 Transcatheter Heart Valves 6.2.1 Market Trends 6.2.2 Market Forecast 6.3 Atherectomy Devices 6.3.1 Market Trends 6.3.2 Market Forecast 6.4 Catheters 6.4.1 Market Trends 6.4.2 Market Forecast 6.5 Balloons 6.5.1 Market Trends 6.5.2 Market Forecast 6.6 Stents 6.6.1 Market Trends 6.6.2 Market Forecast 6.7 Others 6.7.1 Market Trends 6.7.2 Market Forecast 7 Market Breakup by Procedure 7.1 Catheter-Based Valve Implantation 7.1.1 Market Trends 7.1.2 Market Forecast 7.2 Congenital Heart Defect Correction 7.2.1 Market Trends 7.2.2 Market Forecast 7.3 Angioplasty 7.3.1 Market Trends 7.3.2 Market Forecast 7.4 Coronary Thrombectomy 7.4.1 Market Trends 7.4.2 Market Forecast 7.5 Others 7.5.1 Market Trends 7.5.2 Market Forecast 8 Market Breakup by End Use 8.1 Clinical Testing Laboratories 8.1.1 Market Trends 8.1.2 Market Forecast 8.2 Hospitals 8.2.1 Market Trends 8.2.2 Market Forecast 8.3 Cardiac Centers 8.3.1 Market Trends 8.3.2 Market Forecast 8.4 Pediatric Clinics 8.4.1 Market Trends 8.4.2 Market Forecast 8.5 Research Institutions 8.5.1 Market Trends 8.5.2 Market Forecast 9 Market Breakup by Region 10 SWOT Analysis 11 Value Chain Analysis 12 Porters Five Forces Analysis 13 Price Analysis 14 Competitive Landscape 14.1 Market Structure 14.2 Key Players 14.3 Profiles of Key Players 14.3.1 Biotronik SE & Co. KG 14.3.1.1 Company Overview 14.3.1.2 Product Portfolio 14.3.1.3 SWOT Analysis 14.3.2 Boston Scientific Corporation 14.3.2.1 Company Overview 14.3.2.2 Product Portfolio 14.3.2.3 Financials 14.3.2.4 SWOT Analysis 14.3.3 Cardinal Health Inc. 14.3.3.1 Company Overview 14.3.3.2 Product Portfolio 14.3.3.3 Financials 14.3.3.4 SWOT Analysis 14.3.4 Edwards Lifesciences Corporation 14.3.4.1 Company Overview 14.3.4.2 Product Portfolio 14.3.4.3 Financials 14.3.4.4 SWOT Analysis 14.3.5 General Electric Company 14.3.5.1 Company Overview 14.3.5.2 Product Portfolio 14.3.5.3 Financials 14.3.5.4 SWOT Analysis 14.3.6 Koninklijke Philips N.V. 14.3.6.1 Company Overview 14.3.6.2 Product Portfolio 14.3.6.3 Financials 14.3.6.4 SWOT Analysis 14.3.7 Lepu Medical Technology (Beijing) Co. Ltd. 14.3.7.1 Company Overview 14.3.7.2 Product Portfolio 14.3.7.3 Financials 14.3.8 Medtronic plc 14.3.8.1 Company Overview 14.3.8.2 Product Portfolio 14.3.8.3 Financials 14.3.8.4 SWOT Analysis 14.3.9 NuMED Inc. 14.3.9.1 Company Overview 14.3.9.2 Product Portfolio 14.3.10 Siemens Healthineers AG 14.3.10.1 Company Overview 14.3.10.2 Product Portfolio 14.3.10.3 Financials 14.3.10.4 SWOT Analysis 14.3.11 Terumo Corporation 14.3.11.1 Company Overview 14.3.11.2 Product Portfolio 14.3.11.3 Financials 14.3.11.4 SWOT Analysis 14.3.12 W. L. Gore & Associates Inc. 14.3.12.1 Company Overview 14.3.12.2 Product Portfolio 14.3.12.3 SWOT Analysis For more information about this report visit Media Contact: Research and Markets Laura Wood, Senior Manager [email protected] For E.S.T Office Hours Call +1-917-300-0470 For U.S./CAN Toll Free Call +1-800-526-8630 For GMT Office Hours Call +353-1-416-8900 U.S. Fax: 646-607-1904 Fax (outside U.S.): +353-1-481-1716 Logo: SOURCE Research and Markets