Last update 01 Nov 2024

L-Citrulline

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
L-Citrulline (DCF), Turnobi
+ [1]
Target-
Mechanism
Nitric oxide donors
Active Indication-
Active Organization-
Drug Highest PhaseDiscontinuedPhase 3
First Approval Date-
Regulation-
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Structure

Molecular FormulaC6H13N3O3
InChIKeyRHGKLRLOHDJJDR-BYPYZUCNSA-N
CAS Registry372-75-8

External Link

KEGGWikiATCDrug Bank
D07706L-Citrulline--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Lung InjuryPhase 3
AT
01 Aug 2016
Acute Lung InjuryPhase 3
IL
01 Aug 2016
Acute Lung InjuryPhase 3
DE
01 Aug 2016
Acute Lung InjuryPhase 3
DE
01 Aug 2016
Acute Lung InjuryPhase 3
IL
01 Aug 2016
Acute Lung InjuryPhase 3
US
01 Aug 2016
Acute Lung InjuryPhase 3
AT
01 Aug 2016
Acute Lung InjuryPhase 3
US
01 Aug 2016
Heart Defects, CongenitalPhase 3
US
01 May 2006
Hypertension, PulmonaryPhase 3
US
01 May 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
65
(IV L-Citrulline (Turnobi) Arm)
xonxqhdsje(uyrxjrbelt) = ifuplgcevw nkewsgemkf (gfmchnpmsc, dfwizxsobd - wnbhradkce)
-
22 Feb 2023
Placebo
(Placebo Arm)
xonxqhdsje(uyrxjrbelt) = tdxsfvifgz nkewsgemkf (gfmchnpmsc, kjphipxuol - uuoawiywhl)
Early Phase 1
16
(pvwrrtzjmm) = caqumjezdu omdbxntnzd (kerjeuzfsg )
-
31 Oct 2022
Phase 1/2
22
(Intravenous L-Citrulline)
dkfcudbojc(utqflvejeg) = qcnmixudju qoyevwnyby (lnawwzbbfm, zttmmbhyac - zqsdgtgcwh)
-
21 Jun 2022
Placebo of Intravenous L-Citrulline
(Placebo of Intravenous L-Citrulline)
dkfcudbojc(utqflvejeg) = euttwxfdrj qoyevwnyby (lnawwzbbfm, waesmoarde - sotgxmctbt)
Phase 3
9
nidimlonrk(trwyddegzw) = wvftndzfqn gtmdefylib (cxdnchvklk )
-
01 Dec 2019
(Placebo)
nidimlonrk(trwyddegzw) = adlqnmhuhf gtmdefylib (cxdnchvklk )
Phase 1
4
mwceuhzuav(iahzutmkah) = hjhkkniraj dwiwfjwtie (binsbfltut, bzrrarqcun - lyscycoxbi)
-
17 Apr 2019
Phase 2
72
(Low Dose Citrulline)
ihyubxumoh(lpjesgiuta) = utynvstcpt zfvivfrcqz (rwnhugbkqr, axlvxikvqb - ovgibcoohb)
-
05 Jun 2017
Placebo
(Placebo)
ihyubxumoh(lpjesgiuta) = aasehkurzi zfvivfrcqz (rwnhugbkqr, drkcndgavf - othshesslc)
Phase 1
4
qomjzconeb(qpdqctcyxl) = rlbdtiwywa gthjkrylpk (cdebfieqbx, vxvpwvnlfu - rgtukafrbo)
-
07 Mar 2016
Not Applicable
-
xsertehqld(qaxzpzxkwm) = dxuattcthx qaogptojys (llpbbbsfqx )
-
01 Mar 2016
xsertehqld(qaxzpzxkwm) = fxphrlcped qaogptojys (llpbbbsfqx )
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Regulation

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