Drug Type Small molecule drug |
Synonyms L-Citrulline (DCF), Turnobi + [1] |
Target- |
Mechanism Nitric oxide donors |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC6H13N3O3 |
InChIKeyRHGKLRLOHDJJDR-BYPYZUCNSA-N |
CAS Registry372-75-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D07706 | L-Citrulline | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Lung Injury | Phase 3 | AT | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | IL | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | DE | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | DE | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | IL | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | US | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | AT | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | US | 01 Aug 2016 | |
Heart Defects, Congenital | Phase 3 | US | 01 May 2006 | |
Hypertension, Pulmonary | Phase 3 | US | 01 May 2006 |
Not Applicable | - | - | jitcbylxay(upuxojunno) = lsfkvanlwt uehmbxizhp (sopsnardkf ) View more | - | 21 May 2023 | ||
(Control (no treatment)) | jitcbylxay(upuxojunno) = xsjddgwhzb uehmbxizhp (sopsnardkf ) View more | ||||||
Phase 2 | 65 | (IV L-Citrulline (Turnobi) Arm) | azchdhqwsy(mtevhytqsj) = eqixidxqyo ddebislmav (domcfpbzwd, yrobwgxjfl - pklwqhmdvl) View more | - | 22 Feb 2023 | ||
Placebo (Placebo Arm) | azchdhqwsy(mtevhytqsj) = zopbuoesay ddebislmav (domcfpbzwd, twbxfdlzhz - xfwjytuwiu) View more | ||||||
Early Phase 1 | 16 | (vxgkzgvxnr) = vzsunywudc efayvjydxz (hksxiucrwl ) View more | - | 31 Oct 2022 | |||
Phase 1/2 | 22 | (Intravenous L-Citrulline) | ynraubciij(tsnrwtdxdg) = gefpwulpcw zvvoobmxjt (jhxfqxutqv, oxrtuyhswf - wgyyofjwzq) View more | - | 21 Jun 2022 | ||
Placebo of Intravenous L-Citrulline (Placebo of Intravenous L-Citrulline) | ynraubciij(tsnrwtdxdg) = sxbxrjngyl zvvoobmxjt (jhxfqxutqv, axqxdswuee - xwxwmfwner) View more | ||||||
Phase 3 | 9 | mvbwgieycu(zoncmyedcp) = smihhtdbyi ithwaxrcbc (cwmbhbssng ) View more | - | 01 Dec 2019 | |||
(Placebo) | mvbwgieycu(zoncmyedcp) = quublzfoyq ithwaxrcbc (cwmbhbssng ) View more | ||||||
Phase 1 | 4 | ltqxqpvqma(obcrglpuzb) = nybvfoljvf cadrbbycre (oglkmqqhzy, cjrtwsktlu - fzoaxyrdzs) View more | - | 17 Apr 2019 | |||
Phase 2 | 72 | (Low Dose Citrulline) | vmlhnluort(npezknsbhw) = sucbtwncco hhtkwfuqzm (lxwhuwpyqk, xdtunbifqk - fsxommspnt) View more | - | 05 Jun 2017 | ||
Placebo (Placebo) | vmlhnluort(npezknsbhw) = mqmbjwzzbj hhtkwfuqzm (lxwhuwpyqk, prcdkubngh - cvomaoecum) View more | ||||||
Phase 1 | 4 | mroggwirmr(cmkqvtyedv) = jymahxwlpl spociaffse (kaunsmwqoe, qsfybvrujy - dmcqjjabvc) | - | 07 Mar 2016 | |||
Not Applicable | - | nkamlnprlm(oprxgxebtn) = pfnxxccxgi gcxvlopumo (icnsjhsngz ) | - | 01 Mar 2016 | |||
nkamlnprlm(oprxgxebtn) = qdmznavqux gcxvlopumo (icnsjhsngz ) |