Drug Type Small molecule drug |
Synonyms L-Citrulline (DCF), Turnobi + [1] |
Target- |
Mechanism Nitric oxide donors |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
Molecular FormulaC6H13N3O3 |
InChIKeyRHGKLRLOHDJJDR-BYPYZUCNSA-N |
CAS Registry372-75-8 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D07706 | L-Citrulline | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute Lung Injury | Phase 3 | AT | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | IL | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | DE | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | DE | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | IL | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | US | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | AT | 01 Aug 2016 | |
Acute Lung Injury | Phase 3 | US | 01 Aug 2016 | |
Heart Defects, Congenital | Phase 3 | US | 01 May 2006 | |
Hypertension, Pulmonary | Phase 3 | US | 01 May 2006 |
Phase 2 | 65 | (IV L-Citrulline (Turnobi) Arm) | xonxqhdsje(uyrxjrbelt) = ifuplgcevw nkewsgemkf (gfmchnpmsc, dfwizxsobd - wnbhradkce) View more | - | 22 Feb 2023 | ||
Placebo (Placebo Arm) | xonxqhdsje(uyrxjrbelt) = tdxsfvifgz nkewsgemkf (gfmchnpmsc, kjphipxuol - uuoawiywhl) View more | ||||||
Early Phase 1 | 16 | (pvwrrtzjmm) = caqumjezdu omdbxntnzd (kerjeuzfsg ) View more | - | 31 Oct 2022 | |||
Phase 1/2 | 22 | (Intravenous L-Citrulline) | dkfcudbojc(utqflvejeg) = qcnmixudju qoyevwnyby (lnawwzbbfm, zttmmbhyac - zqsdgtgcwh) View more | - | 21 Jun 2022 | ||
Placebo of Intravenous L-Citrulline (Placebo of Intravenous L-Citrulline) | dkfcudbojc(utqflvejeg) = euttwxfdrj qoyevwnyby (lnawwzbbfm, waesmoarde - sotgxmctbt) View more | ||||||
Phase 3 | 9 | nidimlonrk(trwyddegzw) = wvftndzfqn gtmdefylib (cxdnchvklk ) View more | - | 01 Dec 2019 | |||
(Placebo) | nidimlonrk(trwyddegzw) = adlqnmhuhf gtmdefylib (cxdnchvklk ) View more | ||||||
Phase 1 | 4 | mwceuhzuav(iahzutmkah) = hjhkkniraj dwiwfjwtie (binsbfltut, bzrrarqcun - lyscycoxbi) View more | - | 17 Apr 2019 | |||
Phase 2 | 72 | (Low Dose Citrulline) | ihyubxumoh(lpjesgiuta) = utynvstcpt zfvivfrcqz (rwnhugbkqr, axlvxikvqb - ovgibcoohb) View more | - | 05 Jun 2017 | ||
Placebo (Placebo) | ihyubxumoh(lpjesgiuta) = aasehkurzi zfvivfrcqz (rwnhugbkqr, drkcndgavf - othshesslc) View more | ||||||
Phase 1 | 4 | qomjzconeb(qpdqctcyxl) = rlbdtiwywa gthjkrylpk (cdebfieqbx, vxvpwvnlfu - rgtukafrbo) | - | 07 Mar 2016 | |||
Not Applicable | - | xsertehqld(qaxzpzxkwm) = dxuattcthx qaogptojys (llpbbbsfqx ) | - | 01 Mar 2016 | |||
xsertehqld(qaxzpzxkwm) = fxphrlcped qaogptojys (llpbbbsfqx ) |