Last update 01 Nov 2024

Artificial Lens Implant Migration

Last update 01 Nov 2024

Basic Info

Synonyms

Artificial Intra ocular Implant Dislocation, Artificial Intra-ocular Implant Dislocation, Artificial Lens Implant Dislocation

+ [3]

Introduction

The shifting and or tilting of implanted artificial lens resulting in impaired vision.

Drugs associated with Artificial Lens Implant Migration

Sodium Hyaluronate

Target-

Mechanism-

Active Org.

Shandong Bausch & Lomb Freda Pharmaceutical Co. Ltd. [+8]

Originator Org.

Seikagaku Corp.

Active Indication

Keratoplasty rejection [+11]

Inactive Indication-

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

First Approval Date29 Nov 1986

Clinical Trials associated with Artificial Lens Implant Migration

NCT05458661 / Not yet recruitingNot Applicable

Feasibility Investigation of Biometry and Tomography Measurements in a Heterogeneous Patient Cohort (BioBase)

The planned clinical investigation will be conducted to acquire raw data for the development of the algorithm. The data acquisition is intended to obtain first impressions of the potential performance of the changed hardware and software components and to confirm the safety profile assessed by risk analysis.

Start Date01 Aug 2022

Sponsor / Collaborator

Carl Zeiss Meditec AG

100 Clinical Results associated with Artificial Lens Implant Migration

100 Translational Medicine associated with Artificial Lens Implant Migration

0 Patents (Medical) associated with Artificial Lens Implant Migration

Literatures (Medical) associated with Artificial Lens Implant Migration

01 Jun 2024·Journal of Cataract & Refractive Surgery

Lens capsule pathological characteristics in cases of intraocular lens dislocation with atopic dermatitis

Article

Author: Shimoda, Masayuki ; Komatsu, Koji ; Ichihara, Kosuke ; Masuda, Yoichiro ; Nakano, Tadashi ; Kubota, Hoshiho ; Iida, Masanobu ; Iwamoto, Masami ; Kawai, Kenji ; Yamamoto, Naoki ; Iwauchi, Ai

Purpose:To explore lens capsule pathological characteristics in intraocular lens (IOL) dislocation after cataract surgery in patients with atopic dermatitis (AD).Setting:University hospital department of ophthalmology.Design:Case series with clinicopathological correlations.Methods:Lens capsules and surrounding tissues excised during surgery from eyes with AD (AD group) and eyes without AD (non-AD group) with IOL dislocation were histologically evaluated. Hematoxylin and eosin staining was used to assess abnormal changes in lens epithelial cells (LECs). Masson trichrome staining distinguished the fibrous metaplasia around the lens capsule into high-density and low-density fibrosis. Capsular splitting (thinning) was identified in both stained preparations.Results:The IOL dislocation morphology in the AD group (10 eyes of 10 patients) included 7 cases of capsular bag dislocation (CBD) and 3 cases of dead bag syndrome (DBS), with an average duration to IOL dislocation of 11.5 ± 5.6 years. All patients in the non-AD group (12 eyes of 12 patients) had CBD, averaging 10.2 ± 5.7 years to dislocation. Abnormal LECs, low-density fibrosis, and capsular splitting were observed in 9 (90), 9 (90), and 6 (60) of the patients in the AD group compared with 6 (50), 3 (25), and 2 (18), respectively, in the non-AD group (total n [%]).Conclusions:Compared with the non-AD group, the AD group exhibited higher frequencies of morphological changes in LECs, low-density fibrosis around the lens capsule, and capsular splitting characteristics of DBS. These results suggest LEC degeneration and increased lens capsule fragility occurred in patients with AD.

01 Aug 2020·Journal of the American College of Emergency Physicians Open

Recurrent and radiographically unrecognized iatrogenic intra‐prosthesis hip dislocations

Author: Cairns, Stephanie L. ; Jarman, Paul G. ; Fox, Olivia J. K.

AbstractHip dislocation is a common complication after total hip arthroplasty surgery. Newer prosthetic implants aim to reduce the risk of dislocation. The new dual mobility implant has a unique design that may result in intra‐prosthetic dislocation. We report a case of a recurrently missed iatrogenic intra‐prosthetic dislocation following closed reduction efforts in the emergency department (ED). Emergency physicians must be aware of the design, pitfalls, and management of this new prosthetic hip design.

01 Jan 2017·Plastic & Reconstructive SurgeryQ2 · MEDICINE

Staged Suprapectoral Expander/Implant Reconstruction without Acellular Dermal Matrix following Nipple-Sparing Mastectomy

Q2 · MEDICINE

Article

Author: Harness, Jay K ; Salibian, Arthur H ; Mowlds, Donald S

Background:Since the introduction of nipple-sparing mastectomy as an oncologically safe procedure for the treatment of breast cancer, reconstructive efforts for immediate staged expander/implant reconstruction have focused on submuscular implantation with or without acellular dermal matrix. Suprapectoral reconstruction without acellular dermal matrix has received little attention in the reconstructive literature of nipple-sparing mastectomy.Methods:Between 2005 and 2015, 155 patients (250 breasts) underwent nipple-sparing mastectomy with prepectoral staged expander/implant reconstruction using thick mastectomy skin flaps without acellular dermal matrix. Patients with different breast sizes, including those patients with very large breasts who required a primary mastopexy, were considered candidates for the suprapectoral reconstruction. Tumor-related data, comorbidities, and preoperative or postoperative radiation therapy were evaluated for correlation with the final outcome.Results:Patients were followed up for an average of 55.5 months (range, 138.1 to 23.6 months). The tumor recurrence rate was 2.6 percent. Adverse outcomes such as capsular contracture, implant dystopia, and rippling were studied. Aesthetic outcome, based on a three-point evaluation scale, showed 53.6 percent of patients as having a very good result, 31.6 percent showing a good result, 9 percent showing a fair result, and 5.8 percent showing a poor result.Conclusions:The suprapectoral two-stage expander/implant reconstruction without acellular dermal matrix in nipple-sparing mastectomy has certain advantages with respect to breast shape, less morbidity related to expansion, ease of reconstruction, and cost effectiveness. These advantages have to be weighed against those of subpectoral reconstruction with acellular dermal matrix to determine the method of choice.CLINCAL QUESTION/LEVEL OF EVIDENCE:Therapeutic, IV.

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