Last update 01 Nov 2024

Striae gravidarum

Last update 01 Nov 2024

Basic Info

Synonyms

Pregnancy Related Stretch Mark, Pregnancy Stretch Mark, Striae gravidarum

+ [4]

Introduction

The visible, linear scarring in the dermis, predominantly of the abdomen due to the stretching of tissue and related hormonal changes during pregnancy.

Drugs associated with Striae gravidarum

MVR-EX103

Target-

Mechanism-

Active Org.

Shenzhen Yinuowei Medical Technology Co., Ltd.Startup

Originator Org.

Shenzhen Yinuowei Medical Technology Co., Ltd.Startup

Active Indication

Striae gravidarum

Inactive Indication

Pancreatic Cancer

Drug Highest PhaseDiscovery

First Approval Ctry. / Loc.-

First Approval Date20 Jan 1800

Clinical Trials associated with Striae gravidarum

IRCT20240809062706N2 / RecruitingPhase 3IIT

The effect of topical dexpanthenol cream on the prevention of striae in primigravida women: A double-blind randomized controlled trial

Start Date24 Sep 2024

Sponsor / Collaborator

Tabriz University of Medical Sciences

NCT05847530 / RecruitingNot Applicable

Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions

The primary objective of this pilot study is exploratory investigation evaluating the Potenza microneedle fractional radiofrequency (RF) device and may be used in combination with the Icon intense pulsed light (IPL) device.

Start Date01 Sep 2024

Sponsor / Collaborator

Cynosure LLC

NCT06530173 / Not yet recruitingNot ApplicableIIT

Relationship Between Striae Gravidarum and Low-Back Pain Among Pregnant Women: a Cross-Sectional Study

• To improve the quality of pregnant women's lives and provide better control for pregnancy-associated symptoms.

Start Date01 Aug 2024

Sponsor / Collaborator

Assiut University

100 Clinical Results associated with Striae gravidarum

100 Translational Medicine associated with Striae gravidarum

0 Patents (Medical) associated with Striae gravidarum

231

Literatures (Medical) associated with Striae gravidarum

01 Nov 2024·European Journal of Obstetrics & Gynecology and Reproductive Biology

Retraction notice to “Evaluation of the severity of striae gravidarum in women with pelvic organ prolapse” [Eur. J. Obstet. Gynecol. Reprod. Biol. 253 (2020) 21–24]

Article

Author: Ahmed, Amal A ; Ahmed, Amal A. ; Elprince, Mohamed ; Taha, Omima Tharwat

01 Sep 2024·Cureus

Cutaneous Changes During Pregnancy: A Comprehensive Review.

Review

Author: Jawade, Sugat ; Madke, Bhushan ; Kondalkar, Ambika ; Gupta, Shreya N ; Ganjre, Samyak

Pregnancy induces various physiological changes in a woman's body that significantly impact the skin involving the face and trunk. This comprehensive review explores the cutaneous changes in these regions, driven by hormonal, mechanical, and immunological factors. Physiological changes such as hyperpigmentation, striae gravidarum, and vascular alterations are discussed in addition to pathological conditions like acrochordon (skin tags), pemphigoid gestationis, impetigo herpetiformis, and intrahepatic cholestasis of pregnancy. Understanding these changes is essential for healthcare providers to offer appropriate reassurance and management to expectant mothers. This review provides insights into dermatological changes on the face and trunk during pregnancy to contribute to better clinical care and support future research.

20 Aug 2024·Iranian journal of kidney diseases

Acute Kidney Injury in Critically Ill Pregnant Women:A Retrospective Study on Risk Factors and Outcomes.

Article

Author: Song, Qifeng ; Chen, Chen ; Li, Guofu ; Jia, Jia

INTRODUCTIONDespite the significant decline in the incidence of pregnancy-related acute kidney injury (AKI) in recent decades due to advancements in medicine and increased awareness of this disease, it remains an important risk factor for maternal morbidity and mortality. However, as fertilization techniques allow women of advanced age to become pregnant, the incidence of pregnancy-related AKI has increased. Consequently, early identification of and intervention for pregnancy-related AKI are particularly important.METHODSThis was a retrospective clinical analysis. Data were collected from pregnant patients who were treated in the ICU of Shengjing Hospital of China Medical University from January 2014 to June 2020; The patients were divided into two groups based on their kidney function status: AKI and non-AKI. Additionally, they were further categorized into recovered and non-recovered groups based on their prognosis. The Wilcoxon rank sum test and the chi-square test were used for multigroup comparisons, while logistic regression analysis was used for the analysis of risk factors. P < .05 was considered to indicate a statistically significant difference in all correlation analyses.RESULTSAmong 874 pregnant women in this study, 136 had AKI (15.56%), while 36 developed chronic renal insufficiency (26.47%). Statistically significant associations were shown for shock (P = .002), sepsis (P < .001), coagulopathies (P = .001), liver insufficiency (P < .001), postpartum hemorrhage (P = .016), intrauterine fetal death (P = .042) and mechanical ventilation (P = .006) between the AKI-group and the non-AKI group. The development of AKI based on an elevated baseline creatinine level was significantly related to the outcome of renal function (P < .001), while a significant difference was shown in the use of continuous renal replacement therapy (CRRT) between the recovery group and the non-recovery group (P = .023).CONCLUSIONWe identified the relevant risk factors leading to pregnancy-related AKI and affecting the patients' prognosis. Shock, sepsis, coagulation disorders, liver insufficiency, postpartum hemorrhage, intrauterine fetal death and mechanical ventilation are independent risk factors for pregnancy-related AKI, while an elevated baseline creatine level is a key factor for poor prognosis. Meanwhile, early CRRT can effectively reverse renal outcomes.

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