Synonyms BEEC, BEEC - bladder exstrophy, epispadias, cloacal exstrophy complex, BLADDER EXSTROPHY AND EPISPADIAS COMPLEX + [8] |
Introduction A spectrum of genitourinary malformations ranging in severity from epispadias and classical bladder exstrophy to exstrophy of the cloaca as the most severe form. Depending on severity, the disorder may involve the urinary system, the musculoskeletal system, the pelvis, the pelvic floor, the abdominal wall, the genitalia and sometimes the spine and the anus. The underlying cause remains unknown, rare cases of familial occurrence have been reported and both genetic and environmental factors are likely to play a role. |
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Mechanism- |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhasePhase 1/2 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date01 Mar 2020 |
Sponsor / Collaborator |
Start Date01 Feb 2017 |
Sponsor / Collaborator |