Synonyms Isolated Non-compaction of the Ventricular Myocardium, Isolated Noncompaction of the Ventricular Myocardium, X連鎖孤立性左室心筋緻密化障害 + [19] |
Introduction Rare congenital cardiomyopathies characterized by the lack of left ventricular myocardium compaction. The noncompaction results in numerous prominent trabeculations and a loose myocardial meshwork (spongy myocardium) in the LEFT VENTRICLE. Heterogeneous clinical features include diminished systolic function sometimes associated with left ventricular dilation, that presents either neonatally or progressively. Often, the RIGHT VENTRICLE is also affected. CONGESTIVE HEART FAILURE; PULMONARY EMBOLISM; and ventricular ARRHYTHMIA are commonly seen. |
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Drug Highest PhaseApproved |
First Approval Ctry. / Loc. United States |
First Approval Date30 Dec 1988 |
Start Date30 Oct 2024 |
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Start Date21 Dec 2011 |
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Start Date01 Oct 2011 |
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