Synonyms CALCULUS URETERAL, Calculi, Ureteral, Calculus of ureter + [26]  | 
Introduction Stones in the URETER that are formed in the KIDNEY. They are rarely more than 5 mm in diameter for larger renal stones cannot enter ureters. They are often lodged at the ureteral narrowing and can cause excruciating renal colic.  | 
Target-  | 
Mechanism-  | 
Originator Org.  | 
Active Indication  | 
Inactive Indication-  | 
Drug Highest PhaseApproved  | 
First Approval Ctry. / Loc. China  | 
First Approval Date14 Sep 2022  | 
Target  | 
Mechanism ADRA1 antagonists  | 
Active Org.  | 
Originator Org.  | 
Active Indication  | 
Inactive Indication  | 
Drug Highest PhaseApproved  | 
First Approval Ctry. / Loc. Japan  | 
First Approval Date23 Jan 2006  | 
Target-  | 
Mechanism-  | 
Active Org.  | 
Originator Org.  | 
Active Indication  | 
Inactive Indication  | 
Drug Highest PhaseApproved  | 
First Approval Ctry. / Loc. Japan  | 
First Approval Date02 Mar 2005  | 
Start Date01 Mar 2025  | 
Sponsor / Collaborator  | 
Start Date23 Jan 2025  | 
Sponsor / Collaborator  | 
Start Date25 Dec 2024  | 
Sponsor / Collaborator  | 
