Synonyms AHDS, ALLAN-HERNDON SYNDROME, ALLAN-HERNDON-DUDLEY SYNDROME + [26] |
Introduction A rare, X-linked recessive inherited syndrome caused by mutations in the SLC16A2 (MCT8) gene. It affects exclusively males and is characterized by mental retardation, limited mobility, muscle hypoplasia, hypotonia, contractures, and spasticity. |
Target |
Mechanism THR-α agonists [+1] |
Active Org. |
Originator Org.- |
Active Indication |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Target |
Mechanism THR modulators |
Active Org. |
Originator Org.- |
Active Indication |
Inactive Indication- |
Drug Highest PhasePhase 3 |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Target |
Mechanism THR agonists |
Active Org.- |
Originator Org. |
Active Indication- |
Inactive Indication |
Drug Highest PhaseDiscontinued |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date21 Jul 2023 |
Sponsor / Collaborator |
Start Date21 Jul 2023 |
Sponsor / Collaborator |
Start Date06 Jul 2023 |
Sponsor / Collaborator |