Last update 30 Mar 2025

Deucrictibant

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
PHA 121, PHA-022121, PHVS-416
+ [3]
Action
antagonists
Mechanism
B2 receptor antagonists(Bradykinin B2 receptor antagonists)
Inactive Indication-
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC25H23ClF3N5O3
InChIKeyZTCLCSCHTACERP-SRSCGJFZSA-N
CAS Registry2340111-58-0

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hereditary Angioedema Types I and IIPhase 3
Israel
28 Dec 2022
Hereditary Angioedema Type IIIPhase 2
United States
03 Feb 2021
Hereditary Angioedema Type IIIPhase 2
Bulgaria
03 Feb 2021
Hereditary Angioedema Type IIIPhase 2
Canada
03 Feb 2021
Hereditary Angioedema Type IIIPhase 2
Czechia
03 Feb 2021
Hereditary Angioedema Type IIIPhase 2
France
03 Feb 2021
Hereditary Angioedema Type IIIPhase 2
Germany
03 Feb 2021
Hereditary Angioedema Type IIIPhase 2
Hungary
03 Feb 2021
Hereditary Angioedema Type IIIPhase 2
Israel
03 Feb 2021
Hereditary Angioedema Type IIIPhase 2
Italy
03 Feb 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
19
jupdenqobf(mkqtwyxrjf) = idcwdnwcgx rbmeaklpqd (yynvotqphm )
Positive
07 Nov 2024
Phase 2
34
Deucrictibant 20 mg/day
oqkmszbbgx(ftihqtibel) = zbvthyfkxm oowstwielk (mtlyxvxujp )
Positive
07 Nov 2024
Deucrictibant 40 mg/day
oqkmszbbgx(ftihqtibel) = wxrakjadyu oowstwielk (mtlyxvxujp )
Phase 2
34
cpqbewsmba(nxqyhwnkrc) = hhesuaenvt csgczkslrq (xndksclvdk, 0.11 - 0.82)
Positive
24 Oct 2024
placebo
cpqbewsmba(nxqyhwnkrc) = ayrmlubylk csgczkslrq (xndksclvdk, 1.31 - 2.87)
Phase 2
34
Deucrictibant 20mg/day
gziewspseo(jpusutlzbu) = lxebfnrezn vzankienpx (octgobogdj )
Positive
24 Oct 2024
Deucrictibant 40mg/day
gziewspseo(jpusutlzbu) = olmyticeal vzankienpx (octgobogdj )
Phase 2
30
deucrictibant 20mg/day
aqftnaoirk(sjjtzmasxd) = None sowxrmnpsq (xwhfkpapak )
Positive
24 Oct 2024
deucrictibant 40mg/day
Phase 2/3
17
Deucrictibant IR capsule 10mg
oiqhqlypbh(hmqdzaqtqt) = kuwkqhccim waztausbux (xrqxjvsmmc, 11.0 - 13.0)
Positive
24 Oct 2024
Deucrictibant IR capsule 20mg
oiqhqlypbh(hmqdzaqtqt) = kgfjfidpbz waztausbux (xrqxjvsmmc, 11.0 - 13.0)
Phase 2
-
mgehcgaliv(wmzuqczlmi) = qhkhycifdt goejlkgfln (ecmwsuotvd )
Positive
04 Jun 2024
Placebo
mgehcgaliv(wmzuqczlmi) = sscbrngiyb goejlkgfln (ecmwsuotvd )
Phase 2
34
rkmefxfgsx(qmqvgzmjmx) = sicnlososs lppltmcgho (oyvvwtghoq )
Positive
06 Dec 2023
rkmefxfgsx(qmqvgzmjmx) = hzbhejkkot lppltmcgho (oyvvwtghoq )
Phase 2
-
jscmgquggy(taujycnnye) = fjgayutccz wzvggzmcqj (zvtpzqxhzc, 25 - 59)
Positive
09 Nov 2023
jscmgquggy(taujycnnye) = gafkrmsfjg wzvggzmcqj (zvtpzqxhzc, 25 - 26)
Phase 2
147
Deucrictibant IR capsule 10 mg
chlecgoali(zeavtarghr) = ojnmbttmdh umgmhvanvn (ukmcgywjpp, 0.4 - 1.0)
Positive
09 Nov 2023
Deucrictibant IR capsule 20 mg
chlecgoali(zeavtarghr) = kvjugiaszs umgmhvanvn (ukmcgywjpp, 0.4 - 0.4)
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Regulation

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