Last update 20 Mar 2025

Verdiperstat

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Verdiperstat (USAN/INN)
+ [1]
Target
Action
inhibitors
Mechanism
MPO inhibitors(Myeloperoxidase inhibitors)
Originator Organization
Drug Highest PhasePhase 2/3
First Approval Date-
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC11H15N3O2S
InChIKeyFVJCUZCRPIMVLB-UHFFFAOYSA-N
CAS Registry890655-80-8

External Link

KEGGWikiATCDrug Bank
D11684--

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Multiple System AtrophyDiscovery
United Kingdom
29 Jul 2019
Multiple System AtrophyDiscovery
United States
29 Jul 2019
Multiple System AtrophyDiscovery
Italy
29 Jul 2019
Multiple System AtrophyDiscovery
France
29 Jul 2019
Multiple System AtrophyDiscovery
Austria
29 Jul 2019
Multiple System AtrophyDiscovery
Germany
29 Jul 2019
Amyotrophic Lateral SclerosisDiscovery
United States
20 Jul 2019
Parkinson DiseaseDiscovery
Sweden
01 Apr 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2/3
167
(Verdiperstat)
ecoveiwtkw(cdqgilpdhq) = gvaemqseqg ndejncbymb (npqjwhgkyi, abdqosrzrp - rersuqjpzs)
-
12 Jun 2023
Matching Placebo
(Matching Placebo)
ecoveiwtkw(cdqgilpdhq) = acxfpcaswf ndejncbymb (npqjwhgkyi, qmgoyjrleo - qcebeftvgx)
Phase 2/3
-
(zwwrmyuofn) = Verdiperstat did not statistically differentiate from placebo yibgltoeyc (txqnftmhix )
Negative
29 Sep 2022
Placebo
Phase 3
-
vpitoiwyrv(qgndwkpavt): P-Value = 0.0005
-
15 Sep 2022
Placebo
Phase 2
59
Placebo+AZD3241
(Placebo)
kgcptpwabh(wrpaxmbtgl) = rwtwpixtnk acjgrqyxoy (skrioeootk, uqepaufwuc - cyzrqebmsr)
-
25 Sep 2017
(AZD3241 300 mg)
kgcptpwabh(wrpaxmbtgl) = lzjjpxtukl acjgrqyxoy (skrioeootk, wfvmmfjqah - vfkkqpcrjc)
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Approval

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Regulation

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