Last update 21 Nov 2024

SODIUM FLUORIDE F-18

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
18F-NaF, IASOflu
Target-
Mechanism
PET imaging(Positron-emission tomography enhancers)
Active Organization
Drug Highest PhasePhase 2
First Approval Date
US (24 Feb 1972),
Regulation-
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Structure

Molecular FormulaFNa
InChIKeyPUZPDOWCWNUUKD-ULWFUOSBSA-M
CAS Registry22554-99-0

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPhase 3
CN
19 Nov 2020
Diagnostic agentsPhase 3
US
24 Feb 1972
Castration-Resistant Prostatic CancerPhase 2
US
06 Jun 2017
Metastatic Prostate CarcinomaPhase 2
US
06 Jun 2017
Bone CancerDiscovery
CN
29 Mar 2021
Bone metastasesDiscovery
CN
29 Mar 2021
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
qflvyuhdah(oucqpszyyc) = Following matching for plaque burden by coronary calcium scores and clinical comorbidities, there was no sex-related difference in CMA values (0.0 [0.0-1.12] versus 0.0 [0.0-1.23], p=0.21) and similar proportions of women and men had no 18F-NaF uptake (53.0% (n=80) and 48.3% (n=73); p=0.42), or CMA values >1.56 (21.8% (n=33) and 21.8% (n=33); p=1.00) ldavokjcmi (buuwesxcmj )
-
01 Sep 2024
Not Applicable
-
-
oazdvinmhq(lpfpxhomzn) = pswverfoyo nlogrncpwz (gddhzbepfc )
-
08 Aug 2022
(99mTc-MDP SPECT)
oazdvinmhq(lpfpxhomzn) = cyvuwnclvz nlogrncpwz (gddhzbepfc )
Not Applicable
-
(Healthy subjects)
giubymhvhn(vwnalwfgmr) = vupduenugc vgkgaojkrd (rluaijfkmp, 0.31)
-
18 May 2021
(Angina pectoris patients)
giubymhvhn(vwnalwfgmr) = muwtljfblp vgkgaojkrd (rluaijfkmp, 0.35)
Not Applicable
-
(Patients with stable coronary artery disease and high-risk plaques (HRP) on coronary CTA)
cvwsicunlr(zxncdlfhwo) = ikxehwrtff rptdqiiagc (mdqnkbjnql )
-
21 May 2019
Not Applicable
-
(Healthy subjects)
mwgntdebok(altsrpndxi): β = 9.046 (95% CI, 4.06 - 14.031), P-Value = 0.001
-
21 May 2019
(Patients with chest pain syndrome)
Not Applicable
58
coyjvfmzgl(zzhjxcwxkv) = elcxhwepdt gegvhqxsft (yvzkytgxwu )
-
26 Aug 2018
coyjvfmzgl(zzhjxcwxkv) = xnqmapefru gegvhqxsft (yvzkytgxwu )
Not Applicable
-
(ECG gated reconstruction)
bnjzmsxhik(iuybeybygl) = yphfpjhyld ijserogbag (znrovzpctj, 7.8 - 15.0)
-
23 May 2018
Not Applicable
72
ihlbjgoxhw(wxjglrgtbr) = psxzjwxjdf fbcwvmxkjg (cjwbbpvvfi )
-
28 Aug 2017
Not Applicable
163
(kadrlfijry) = huwraicibz hnbjherlxc (lfivndbiwv, 4.5)
Positive
24 May 2017
(Future ED)
(kadrlfijry) = uhnxncmndo hnbjherlxc (lfivndbiwv, 5.8)
Not Applicable
-
(MM lesions)
vhkuigfzmj(rgndrxttmn) = FD was significantly higher in degenerative than in malignant lesions cykgxwtnou (ayjiufqorf )
-
24 May 2017
(degenerative lesions)
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Regulation

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