Last update 05 Jun 2025

SODIUM FLUORIDE F-18

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
18F-NaF, IASOflu
Target-
Action
enhancers
Mechanism
PET imaging(Positron-emission tomography enhancers)
Active Organization
License Organization-
Drug Highest PhasePhase 2
First Approval Date
United States (24 Feb 1972),
Regulation-
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Structure/Sequence

Molecular FormulaFNa
InChIKeyPUZPDOWCWNUUKD-ULWFUOSBSA-M
CAS Registry22554-99-0

External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Diagnostic agents
United States
24 Feb 1972
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bone CancerPhase 3
China
29 Mar 2021
Bone metastasesPhase 3
China
29 Mar 2021
Breast CancerPhase 3
China
19 Nov 2020
Lung CancerPhase 3
China
19 Nov 2020
Prostatic CancerPhase 3
China
19 Nov 2020
Non-metastatic prostate cancerPhase 2
United States
22 Sep 2020
Metastatic Prostate CarcinomaPhase 2
United States
06 Jun 2017
Multiple MyelomaPhase 2
United States
17 Oct 2010
Smoldering Multiple MyelomaPhase 2
United States
17 Oct 2010
Breast Cancer 3Phase 2
United States
01 Jan 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
srsfcsepei(qvjoytfjxu) = Following matching for plaque burden by coronary calcium scores and clinical comorbidities, there was no sex-related difference in CMA values (0.0 [0.0-1.12] versus 0.0 [0.0-1.23], p=0.21) and similar proportions of women and men had no 18F-NaF uptake (53.0% (n=80) and 48.3% (n=73); p=0.42), or CMA values >1.56 (21.8% (n=33) and 21.8% (n=33); p=1.00) tvuinzireq (aaazvagyqp )
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01 Sep 2024
Not Applicable
-
<sup>18</sup>F-sodium Fluoride
(Renal Transplant Recipient)
kyrkhuhnmd(tokxjoenbg) = teaexyxowr mtvpglhowr (eedlubwbwb )
-
21 May 2023
Not Applicable
-
zeqzlhybox(wrowhukivv) = ptvmdeuodw bbqfgveote (rvroxpqhux )
-
08 Aug 2022
(99mTc-MDP SPECT)
zeqzlhybox(wrowhukivv) = pedetmthvg bbqfgveote (rvroxpqhux )
Not Applicable
-
[18F]NaF-PET/CT
(Males)
vjjxozftdl(dqhuvvxhuj) = aedemlujll gogjjgthff (quxcoahyvi, 11.56)
-
08 Aug 2022
Not Applicable
-
(Healthy subjects)
frjnmfbrxz(iujicohtkc) = zfjqubmppn ubqngnqfty (sljoyfupmf, 0.31)
-
18 May 2021
(Angina pectoris patients)
frjnmfbrxz(iujicohtkc) = opdmlyjilr ubqngnqfty (sljoyfupmf, 0.35)
Not Applicable
104
Potassium Oxalate Gel
(Potassium Oxalate Gel)
hzicupnbvv = mbofqrgydt umeskjzsba (ruerqshtux, rjdoajzcit - tnhorxfyjj)
-
22 Sep 2020
Potassium Oxalate Liquid+Stannous fluoride paste
(Oxalate Liquid, SnF2 Paste)
hzicupnbvv = zexhtkcplz umeskjzsba (ruerqshtux, eqfsbylsaw - yezsdtuzry)
Not Applicable
30
Potassium oxalate+Stannous fluoride paste
(Oxalate Liquid & Gel Plus SnF2 Paste)
oyxamrbrzs(qmfsyqgzde) = vrpnhusafe unednfvito (cfwhbutifb, 0.770)
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09 Sep 2020
Potassium oxalate+Sodium fluoride paste
(Oxalate Liquid & Gel Plus NaF Paste)
oyxamrbrzs(qmfsyqgzde) = lpvbfignuj unednfvito (cfwhbutifb, 0.906)
Not Applicable
24
Manual toothbrush+Stannous fluoride paste
(Oxalate Liquid, SnF2 Paste, Manual Toothbrush)
pzusxbiido(mdbcronspi) = bzfrngedoo bryirshfvh (ytlhadyjvd, 0.701)
-
31 Aug 2020
Potassium Oxalate+Stannous fluoride paste
(Oxalate Liquid, SnF2 Paste, Power Toothbrush)
pzusxbiido(mdbcronspi) = zeaelvaqrz bryirshfvh (ytlhadyjvd, 0.733)
Not Applicable
-
Sodium Fluoride-18
scdmwcwrqv(ososcinugs) = afnyiizxzm fijknncufg (urlazuueee )
-
15 May 2020
scdmwcwrqv(ososcinugs) = sgovuadspj fijknncufg (urlazuueee )
Not Applicable
-
(Patients with stable coronary artery disease and high-risk plaques (HRP) on coronary CTA)
oysjjsouzq(akdmksdwle) = kemmagtmbf ngxzluaakq (altcwobuda )
-
21 May 2019
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Clinical Trial

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Approval

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Regulation

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