Drug Type Small molecule drug |
Synonyms PF 5212377, PF-5212377, SAM-760 + [1] |
Target |
Mechanism 5-HT6 receptor antagonists(Serotonin 6 (5-HT6) receptor antagonists) |
Therapeutic Areas |
Active Indication- |
Inactive Indication |
Originator Organization |
Active Organization- |
Inactive Organization |
Drug Highest PhaseDiscontinuedPhase 2 |
First Approval Date- |
Regulation- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
- | - | - |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Alzheimer Disease | Phase 2 | US | 01 Nov 2012 | |
Alzheimer Disease | Phase 2 | CA | 01 Nov 2012 | |
Alzheimer Disease | Phase 2 | CL | 01 Nov 2012 | |
Alzheimer Disease | Phase 2 | FR | 01 Nov 2012 | |
Alzheimer Disease | Phase 2 | DE | 01 Nov 2012 | |
Alzheimer Disease | Phase 2 | ES | 01 Nov 2012 | |
Alzheimer Disease | Phase 2 | GB | 01 Nov 2012 | |
Neuropsychiatric syndrome | Phase 2 | US | 01 Nov 2012 | |
Neuropsychiatric syndrome | Phase 2 | CA | 01 Nov 2012 | |
Neuropsychiatric syndrome | Phase 2 | CL | 01 Nov 2012 |
Phase 1 | - | 12 | rnxgdquuix(yuezjiridm) = wkoureikor bkplulidmu (hlewgbureu ) View more | - | 24 Feb 2023 | ||
NCT01712074 (Pubmed) Manual | Phase 2 | 186 | donepezil+PF-05212377 | gsqekexoip(lzjkinmowp): difference = 0.70, P-Value = 0.43 View more | Negative | 05 Apr 2018 | |
donepezil+Placebo | |||||||
Phase 2 | 186 | Placebo | axdnkcjysl(wddtmtzcrw) = przjvlxkid dtbziilpkw (svjefhtbzp, uqingptnol - wywivkmvyx) View more | - | 20 Mar 2017 | ||
Not Applicable | 342 | btgctdjyif(nvlngzccov) = nhclpwmuir vzccultskr (wjggdrxvsc ) View more | Negative | 01 Jul 2016 | |||
Not Applicable | - | pdpflwqxlk(bnxnmarsao) = The most frequently reported treatment emergent AEs was headache twaauhpdib (llabwpqmpb ) View more | - | 01 Jul 2011 | |||
Placebo |