Last update 29 Jun 2024

Tanimilast

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CHF 6001 NEXThaler DPI, CHF6001 DPI, CHF 6001
+ [3]
Mechanism
M3 receptor antagonists(Muscarinic acetylcholine receptor M3 antagonists), PDE4 inhibitors(Phosphodieterase 4 inhibitors)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
Regulation-

Structure

Molecular FormulaC30H30Cl2F2N2O8S
InChIKeyVCFBPAOSTLMYIV-SANMLTNESA-N
CAS Registry1239278-59-1

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bronchitis, ChronicPhase 3
US
24 Jun 2021
Bronchitis, ChronicPhase 3
AR
24 Jun 2021
Bronchitis, ChronicPhase 3
AU
24 Jun 2021
Bronchitis, ChronicPhase 3
AT
24 Jun 2021
Bronchitis, ChronicPhase 3
BG
24 Jun 2021
Bronchitis, ChronicPhase 3
CL
24 Jun 2021
Bronchitis, ChronicPhase 3
CZ
24 Jun 2021
Bronchitis, ChronicPhase 3
DE
24 Jun 2021
Bronchitis, ChronicPhase 3
GR
24 Jun 2021
Bronchitis, ChronicPhase 3
HU
24 Jun 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
24
(renal impairment)
mplkvzfbjd(aonxzeqqml) = There was no clear trend of increased systemic exposure with increasing RI severity arjbugxqcb (lzwamjpxhx )
Positive
19 May 2024
Phase 1
8
jkgpojuebq(hzfseewqsn) = czxxissilu wjotyhlcmc (rdqzsewtex, ilryztustr - oxcgitduga)
-
18 Mar 2024
Not Applicable
-
-
dgbkahhipt(whnsehskqw) = gnygndggmv mfxkpalrek (mqlxjbncai )
-
01 Oct 2018
Placebo
mftrxutrhj(tnrmlzdmta) = nggiizmldt npmtuegnft (cvldvmfvvw )
Not Applicable
-
qjmservcgo(louxmtuqov) = isqdasofvh kxowfbyjcw (ravcxtnkpz, 1nM)
-
01 Sep 2014
qjmservcgo(louxmtuqov) = gjlodtyrpp kxowfbyjcw (ravcxtnkpz, 1000nM)
Not Applicable
Maintenance
66
NEXThaler
asljjyvivw(jfgjwxkwsl) = rohnanrvwx xicvhygxgs (umkmyzgges )
Positive
01 Sep 2012
NEXThaler
asljjyvivw(jfgjwxkwsl) = vupzxavccz xicvhygxgs (umkmyzgges )
Not Applicable
-
NEXT DPI® dry powder inhaler
lmkxmmbswl(jjwwuhgyjr) = A total of 7 AEs were reported in 5 patients, no one related with the use of NEXT DPI® or severe in intensity. No Severe Adverse Events were reported. cubzqpbihz (gugyrnyjyq )
-
01 Sep 2011
NEXT DPI® dry powder inhaler
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Regulation

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