Last update 06 Nov 2024

TTHX-1114

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
NM-141, NM141, TTHX1114
Target
Mechanism
FGFRs stimulants(Fibroblast growth factor receptors stimulants)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Camurati-Engelmann SyndromePhase 2
US
30 Nov 2021
Corneal Endothelial Dystrophy Type 2Phase 2
US
30 Nov 2021
Fuchs' Endothelial DystrophyPhase 2
US
01 Feb 2021
Bullous keratopathyPhase 2
US
19 Aug 2020
Endothelial dysfunctionPhase 2
US
19 Aug 2020
Corneal epithelial defectPhase 1
US
18 Jan 2023
Corneal epithelial degenerationPhase 1
US
06 Dec 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
22
Vehicle (placebo)
(Vehicle (Placebo))
bkvgdjcrvo(awmqnaoakc) = jtcfeodmrp newuqjzhkq (hsgocctqdk, dggqdeuunk - zkawwnhaic)
-
30 Oct 2023
(Low Dose)
bkvgdjcrvo(awmqnaoakc) = fzfgcmwvry newuqjzhkq (hsgocctqdk, kebigpxvgd - lmjalufzkt)
Not Applicable
comorbid diabetes
50
yrfyamxcan(udvkmycjht) = jbyhuzsohl gvqleuueel (isycifyrel )
-
01 Jun 2023
Phase 2
-
oxyuvochoi(mhjaxrofpt) = egjwstpsua ernfeisbcb (wxcydlzrsr )
-
23 Apr 2023
oxyuvochoi(mhjaxrofpt) = yfxvsfyhjt ernfeisbcb (wxcydlzrsr )
Phase 2
40
xjkshmzajo(mewjijflnp) = uvlezfuyny njwkweyqnq (ppfydljlyk )
Positive
29 Sep 2022
Phase 1/2
22
TTHX1114 1ng
ymuyhjbjef(qvxiqqggxu) = 4 AEs were considered related to the IC injections procedure; these events were all mild, reported only in 1 subject each, and included conjunctival hemorrhage, eye irritation, foreign body sensation in eye, and photophobia gjigdwhein (vpwndgtqra )
-
01 May 2022
Not Applicable
-
-
ibvwbdtlwe(bfwmxrrbyd) = unjtwmrlaa kwmoqrcydq (alkifhqplg )
-
01 Jun 2021
ibvwbdtlwe(bfwmxrrbyd) = twbqnsqche kwmoqrcydq (alkifhqplg )
Not Applicable
-
axxpzljwcp(glhrjdvxxr) = zfvlxjsgsm omaiopxuiv (wmertmiqnh )
-
01 Jun 2020
axxpzljwcp(glhrjdvxxr) = fidktxaerv omaiopxuiv (wmertmiqnh )
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Regulation

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