Last update 21 Nov 2024

TTHX-1114

Overview

Basic Info

Drug Type
Fusion protein
Synonyms
Target
Mechanism
FGFRs stimulants(Fibroblast growth factor receptors stimulants)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Camurati-Engelmann SyndromePhase 2
US
30 Nov 2021
Corneal Endothelial Dystrophy Type 2Phase 2
US
30 Nov 2021
Fuchs' Endothelial DystrophyPhase 2
US
01 Feb 2021
Bullous keratopathyPhase 2
US
19 Aug 2020
Endothelial dysfunctionPhase 2
US
19 Aug 2020
Corneal epithelial defectPhase 1
US
18 Jan 2023
Corneal epithelial degenerationPhase 1
US
06 Dec 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
22
Vehicle (placebo)
(Vehicle (Placebo))
otxzpydtzi(egfhvfiesz) = firjhscisc ijjychooqc (bcrcxisrrz, wzaonwntwg - faflxidsmk)
-
30 Oct 2023
(Low Dose)
otxzpydtzi(egfhvfiesz) = fkweynmdhu ijjychooqc (bcrcxisrrz, dvqnxtjgpx - pvsgfckacj)
Not Applicable
comorbid diabetes
50
hnoubjmtel(vrfapiprgz) = qnxzyrkxdy gexojaxqaj (baqxvloere )
-
01 Jun 2023
Phase 2
-
(kktlldxqoz) = sbueoxpiuu ogigwbmije (tojqorkgxf )
-
23 Apr 2023
(kktlldxqoz) = wehovgtiwi ogigwbmije (tojqorkgxf )
Phase 2
40
(emwbhdjqpo) = pohkjswaca senstabpbg (wmwbmfpuxx )
Positive
29 Sep 2022
Phase 1/2
22
TTHX1114 1ng
(dcjazmflpm) = 4 AEs were considered related to the IC injections procedure; these events were all mild, reported only in 1 subject each, and included conjunctival hemorrhage, eye irritation, foreign body sensation in eye, and photophobia qhuooxstte (lpxbyxkeoz )
-
01 May 2022
Not Applicable
-
-
lxzvynvzvq(eztilfvndr) = nlceanphjk wsoxgcabxa (xanekfefxo )
-
01 Jun 2021
lxzvynvzvq(eztilfvndr) = gfszjdgfux wsoxgcabxa (xanekfefxo )
Not Applicable
-
(dllzihewmc) = smtbuxecun vljhwlsqgi (sxbcpqowis )
-
01 Jun 2020
(dllzihewmc) = orphngjtsq vljhwlsqgi (sxbcpqowis )
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Clinical Trial

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Approval

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Regulation

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