Last update 07 Nov 2024
Recombinant Human nsIL12 Oncolytic Adenovirus(VacV Biotheraputics)
Last update 07 Nov 2024
Overview
Basic Info
Drug Type Oncolytic virus |
Synonyms Ad-TD-nsIL12, BioTTT001 |
Target |
Mechanism IL-12R stimulants(Interleukin-12 receptor stimulants) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization  VacV Biotheraputics (UK) LtdStartup |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 2 |
First Approval Date- |
Regulation- |
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Related
4
Clinical Trials associated with Recombinant Human nsIL12 Oncolytic Adenovirus(VacV Biotheraputics)A Clinical Study to Evaluate the Safety and Efficacy of Recombinant Human nsIL12 Oncolytic Adenovirus Injection (BioTTT001) in Combination With SOX and Toripalimab in Patients With Peritoneal Metastases From Gastric Cancer
A Clinical Study to Evaluate the Safety and Efficacy of Recombinant Human nsIL12 Oncolytic Adenovirus Injection (BioTTT001) in Combination With Toripalimab and Regorafenib in Patients With Liver Metastases From Colorectal Cancer
Phase I Clinical Study on the Safety, Tolerability, and Pharmacokinetics of Recombinant Human nsIL12 Oncolytic Adenovirus Injection (BioTTT001) in Patients With Malignant Solid Tumors
100 Clinical Results associated with Recombinant Human nsIL12 Oncolytic Adenovirus(VacV Biotheraputics)
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100 Translational Medicine associated with Recombinant Human nsIL12 Oncolytic Adenovirus(VacV Biotheraputics)
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100 Patents (Medical) associated with Recombinant Human nsIL12 Oncolytic Adenovirus(VacV Biotheraputics)
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100 Deals associated with Recombinant Human nsIL12 Oncolytic Adenovirus(VacV Biotheraputics)
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R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Metastatic Gastric Carcinoma | Phase 2 | - | 02 Apr 2024 | |
| Secondary malignant neoplasm of peritoneum | Phase 2 | - | 02 Apr 2024 | |
| Colorectal Liver Metastases | Phase 1 | - | 02 Apr 2024 | |
| Metastatic Colorectal Carcinoma | Phase 1 | - | 02 Apr 2024 | |
| Advanced Malignant Solid Neoplasm | Phase 1 | CN | 28 Nov 2023 | |
| Head and Neck Neoplasms | Preclinical | CN | 30 Jan 2022 | |
| Melanoma | Preclinical | CN | 30 Jan 2022 |
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